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Pooled Kaplan-Meier curves showing the cumulative risk of all-cause mortality (a), rehospitalization (b), and cardiovascular death (c) for patients with moderate/severe PVL measured by echocardiography. Pooled Kaplan-Meier curves accompanied by their respective time-varying HRs with 95% CI at every given time during follow-up; these are derived from flexible parametric survival models with B-splines.
Abbreviations: CI, confidence interval; HR, hazard ratio; PVL, paravalvular leak.
