Table 2.
Association of VECAC and CDAI with CVD mortality among patients with CKD in the NHANES (2007–2018).
VCEAC |
CDAI |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Q1 | Q2 |
Q3 |
Q4 |
Q1 | Q2 |
Q3 |
Q4 |
|||||||
HR (95% CI) |
p Value | HR (95% CI) |
p Value | HR (95% CI) |
p Value | HR (95% CI) |
p Value | HR (95% CI) |
p Value | HR (95% CI) |
p Value | |||
CKD 1–2 stage | ||||||||||||||
Model1 | Ref | 0.74(0.49–1.10) | .135 | 0.77(0.52–1.13) | .184 | 0.83(0.55–1.25) | .364 | Ref | 1.01(0.68–1.51) | .957 | 1.12(0.72–1.74) | .620 | 1.11(0.70–1.76) | .661 |
Model2 | Ref | 0.76(0.51–1.13) | .172 | 0.55(0.35–0.87) | .010 | 0.69(0.45–1.04) | .077 | Ref | 0.85(0.51–1.40) | .520 | 0.75(0.44–1.27) | .278 | 0.84(0.48–1.49) | .559 |
Model3 | Ref | 0.82(0.54–1.25) | .352 | 0.51(0.32–0.81) | .004 | 0.64(0.40–1.01) | .057 | Ref | 0.82(0.50–1.36) | .444 | 0.73(0.43–1.24) | .244 | 0.82(0.46–1.47) | .501 |
CKD 3–5 stage | ||||||||||||||
Model1 | Ref | 0.95(0.53–1.71) | .858 | 1.05(0.56–1.97) | .884 | 1.10(0.56–2.15) | .791 | Ref | 1.36(0.80–2.32) | .251 | 1.64(0.97–2.79) | .066 | 1.64(0.97–2.77) | .066 |
Model2 | Ref | 1.04(0.55–1.96) | .902 | 0.87(0.51–1.48) | .604 | 1.01(0.55–1.87) | .969 | Ref | 1.14(0.68–1.90) | .615 | 1.44(0.84–2.48) | .186 | 1.29(0.73–2.27) | .381 |
Model3 | Ref | 1.08(0.55–2.13) | .813 | 0.79(0.46–1.39) | .418 | 1.01(0.50–2.02) | .981 | Ref | 1.27(0.75–2.13) | .370 | 1.58(0.92–2.71) | .097 | 1.36(0.79–2.36) | .267 |
VCEAC: Vitamin C Equivalent Antioxidant Capacity; CDAI: Component Dietary Antioxidant Index; HR: hazard ratio; CI: confidence interval; Q: quartile.
Notes: Model1: adjusted for age, sex, ethnicity, income, and education level. Model 2: Model1 + potassium, protein, carbohydrates, dietary fiber, total fat, alcohol intake, smoking, and MET-PA, and total energy intake was adjusted via the residual method; Model3: Model2 + diabetes, hypertension, CVD and cancer, urine albumin, eGFR, BMI.