Table IV.
Adjusted odds ratios (ORs) with 95% CIs for asthma attacks and emergency care visits for asthma in the past 12 months by serum log2 PFAS concentrations (ng/mL), overall and stratified by sex
| Type of PFAS | Overall |
Male |
Female |
||||||
|---|---|---|---|---|---|---|---|---|---|
| No. | Adjusted OR (95% CI) | P | No. | Adjusted OR (95% CI) | P | No. | Adjusted OR (95% CI) | P | |
| Asthma attack in past 12 months | |||||||||
| PFOS | 859 | 1.08 (0.95, 1.22) | .22 | 371 | 1.18 (0.95, 1.48) | .13 | 488 | 1.01 (0.85, 1.19) | .93 |
| PFOA | 859 | 1.16 (1.01, 1.33) | .04 | 371 | 1.23 (0.94, 1.61) | .13 | 488 | 1.10 (0.90, 1.34) | .35 |
| PFHxS | 1010 | 1.05 (0.93, 1.17) | .43 | 421 | 1.00 (0.80, 1.25) | .99 | 589 | 1.06 (0.92, 1.23) | .41 |
| PFNA | 1010 | 1.11 (0.96, 1.28) | .17 | 421 | 1.17 (0.91, 1.52) | .22 | 589 | 1.07 (0.87, 1.32) | .51 |
| Me-PFOSA-AcOH | 1010 | 1.10 (0.99, 1.23) | .08 | 421 | 1.21 (0.99, 1.49) | .07 | 589 | 1.03 (0.90, 1.18) | .68 |
| PFDA | 1010 | 1.21 (1.03, 1.43) | .02 | 421 | 1.36 (1.05, 1.75) | .02 | 589 | 1.14 (0.92, 1.43) | .23 |
| Emergency care visit for asthma in past 12 months | |||||||||
| PFOS | 859 | 0.99 (0.79, 1.23) | .90 | 371 | 1.14 (0.70, 1.86) | .59 | 488 | 0.91 (0.67, 1.24) | .54 |
| PFOA | 859 | 1.03 (0.77, 1.38) | .85 | 371 | 1.45 (0.64, 3.30) | .37 | 488 | 0.88 (0.62, 1.25) | .47 |
| PFHxS | 1010 | 1.02 (0.86, 1.20) | .85 | 421 | 1.15 (0.69, 1.93) | .59 | 589 | 0.97 (0.81, 1.15) | .70 |
| PFNA | 1010 | 1.00 (0.78, 1.28) | .99 | 421 | 1.12 (0.64, 1.97) | .69 | 589 | 0.98 (0.74, 1.28) | .86 |
| Me-PFOSA-AcOH | 1010 | 0.96 (0.78, 1.18) | .70 | 421 | 1.37 (0.90, 2.10) | .14 | 589 | 0.82 (0.63, 1.06) | .13 |
| PFDA | 1010 | 1.09 (0.86, 1.39) | .48 | 421 | 1.39 (0.86, 2.25) | .18 | 589 | 0.99 (0.74, 1.34) | .97 |
Adjusted for age, sex, race, ethnicity, body mass index, income-to-poverty ratio, and serum cotinine.
Me-PFOSA-AcOH, 2-(N-methyl-PFOSA) acetic acid; PFHxS, perfluorohexane sulfonic acid; PFNA, perfluorononanoic acid.