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a(a) After i.v. injection, Lipo@IR780/L012 nanoparticles circulate in blood and emit blue light to the surrounding for optogenetic stimulation of opsin-expressing neurons under FUS irradiation; the diagram is created using Biorender.com. (b) Mechanism of light emission of Lipo@IR780/L012 nanoparticles under FUS irradiation.
