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. 2023 Jun 2;3(6):e0001974. doi: 10.1371/journal.pgph.0001974

Table 1. Annual changes in characteristics of children hospitalized with an RSV infection.

2018 (n = 267) 2019 (n = 285) 2020 (n = 19) 2021 (n = 263) P-value
Age: months, n (%)
    <3 months 77 (28.8) 70 (24.6) 3 (15.8) 73 (27.8) 0.674
    3–5 months 30 (11.2) 33 (11.6) 3 (15.8) 44 (16.7) 0.0472
    6–11 months 39 (14.6) 45 (15.8) 5 (26.3) 31 (11.8) 0.168
    12–23 months 87 (32.6) 89 (31.2) 5 (26.3) 50 (19.0) 0.000123
    ≥24 months 34 (12.7) 48 (16.8) 3 (15.8) 65 (24.7) 0.000919
Sex: male, n (%) 153 (57.3) 153 (53.7) 10 (52.6) 142 (54.0) 0.765
Palivizumab indication
    n (%) 8(3.0) 4 (1.4) 0 (0) 2 (0.8) 0.246
    not indicated 259 (97.0) 281 (98.6) 19 (100.0) 261 (99.2)
Palivizumab prophylaxis
    n (%) 5 (1.9) 2 (0.7) 0 (0) 0 (0) 0.105
    not administered 262 (98.1) 283 (99.3) 19 (100.0) 263 (100.0)
Presence of siblings
    n (%) 151 (56.6) 164 (57.5) 10 (52.6) 187 (71.1) 0.0154
    no siblings 45 (16.9) 44 (15.4) 4 (21.1) 31 (11.8)
    unknown 71 (26.6) 77 (27.0) 5 (26.3) 45 (17.1)
Hospitalization duration
    mean days (SD) 5.31 (1.97) 5.50 (2.17) 5.58 (1.61) 5.52 (2.50) 0.535
Oxygen use rate, n (%) 107 (40.1) 122 (42.8) 6 (31.6) 122 (46.4) 0.175
HFNC use rate, n (%) 17 (6.4) 25 (8.8) 2 (10.5) 36 (13.7) 0.00784
Ventilator use rate, n (%) 2 (0.7) 1 (0.4) 0 (0) 3 (1.1) 0.386
Mortality rate, n (%) 0 (0) 0 (0) 0 (0) 1 (0.4) NA

HFNC, high-flow nasal cannula; RSV, respiratory syncytial virus; SD, standard deviation