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. Author manuscript; available in PMC: 2024 Apr 6.
Published in final edited form as: Structure. 2023 Mar 16;31(4):480–491.e4. doi: 10.1016/j.str.2023.02.009

Figure 6. L9 recognizes a 27-residue stretch of CSP, which is conserved in most P. falciparum isolates.

Figure 6.

(A, B, C) Sequence logo plot and dendrogram showing sequence conservation of L9 epitope in field isolates of Plasmodium falciparum. Some common strains are highlighted. The scale bar represents number of substitutions per site. (D) Association details of atypical trimeric. Surface representation highlighting PfCSP in purple with ~28 Å distance between the two termini. The fourth Fab (shown in red) was modelled to extend the same interactions as observed in prior protomers, it clashed with Fabs A and C.