KEY RESOURCES TABLE
| REAGENT or RESOURCE | SOURCE | IDENTIFIER |
|---|---|---|
| Chemicals, Peptides, and Recombinant Proteins | ||
| Recombinant PfCSP | Produced in house | N/A |
| L9 IgG | Produced in house | N/A |
| L9 Fab | Produced in house | N/A |
| L9 IgM | Produced in house | N/A |
| Biotinylated junctional peptide I | Genscript | Order ID:# U134AFB120 |
| Biotinylated junctional peptide II | Genscript | Order ID:# U134AFB120 |
| Biotinylated junctional peptide III | Genscript | Order ID:# U134AFB120 |
| Biotinylated junctional peptide IV | Genscript | Order ID:# U134AFB120 |
| Critical Commercial Assays | ||
| Streptavidin Donor Beads, for AlphaLISA | PerkinElmer | CAT#:6760002 |
| Anti-human Fc Acceptor Beads, for AlphaLISA | PerkinElmer | CAT#:AL103M |
| Octet® Streptavidin (SA) Biosensor | Sartorius | CAT#:18-5019 |
| Octet® Anti-Human Fc Capture (AHC) Biosensors | Sartorius | CAT#:18-5060 |
| Deposited Data | ||
| PDB file | This paper | 8EK1 |
| PDB file | This paper | 8EKA |
| EMDB file | This paper | 28192 |
| EMDB file | This paper | 28196 |
| Experimental Models: Cell Lines | ||
| Human: Expi293 cell | Thermo Fisher Scientific | Cat#A14527 |
| Experimental Models: Organisms/Strains | ||
| Mouse: B6(Cg)-Tyrc-2J/J albino | The Jackson Laboratory | JAX:000058 |
| Mouse: Balb/c | The Jackson Laboratory | JAX:000651 |
| Sporozoite: P. berghei sporozoite expressing PfCSP, GFP, and luciferase | Flores-Garcia et al., 2019 | N/A |
| Recombinant DNA | ||
| Plasmodium falciparum circumsporozoite protein (clone 3D7) | PlasmoDB | PF3D7_0304600.1 |
| pVRC8400 huIgG1 | Genscript | N/A |
| pVRC8400 huIgK | Genscript | N/A |
| Software and Algorithms | ||
| Prism 9.0.1 | GraphPad | https://www.graphpad.com/ |
| Microsoft Office | Microsoft | https://www.office.com/ |
| IMGT/V-quest | Brochet et al., 2008 | https://www.imgt.org/IMGTindex/V-QUEST.php |
| Geneious 2020.2 | Biomatters | https://www.geneious.com |
| cryoSPARC v3.3.1 | Punjani et al., 2017 | https://cryosparc.com/ |
| Coot v0.9.4 | Emsley et al., 2004 | https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/ |
| ChimeraX v1.2.5 | Goddard et al., 2018 | https://www.cgl.ucsf.edu/chimerax/docs/user/index.html |
| Phenix v1.18.2 | Adams et al., 2010 | https://www.ks.uiuc.edu/Development/Download/download.cgi?PackageName=NAMD |
| EMRinger | Barad et al., 2015 | http://emringer.com/ |
| MolProbity | Williams et al., 2018 | http://molprobity.biochem.duke.edu |
| PISA | Krissinel and Henrick, 2007 | https://www.ebi.ac.uk/pdbe/pisa/ |
| The PyMOL Molecular Graphics System | Schrödinger, LLC | https://pymol.org/2/ |
| Gene-specific substitution profile | Sheng et al., 2017 | https://cab-rep.c2b2.columbia.edu/ |
| Other | ||
| IVIS® Spectrum In Vivo Imaging System | PerkinElmer | N/A |
| SpectraMax® i3x | Molecular Devices | N/A |