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. 2023 May 22;19(5):e1011415. doi: 10.1371/journal.ppat.1011415

Fig 5. The role of the rvv system in host colonization.

Fig 5

(A, B, C). The competitive index (CI) of indicated mutant strains was analyzed and compared to the CI of wild type during colonization of the infant mouse intestine. Each data point represents the CI in an individual mouse. (A, B) Statistical significance was determined using a One-Way ANOVA and post-hoc Tukey’s multiple comparisons test. Means from individual biological replicates (n ≥ 6) were compared to that of wild type, and differences with an adjusted P value of ≤ 0.01 were deemed significant. ***, P ≤ 0.0001. (C) Means from at least six biological replicates were compared by an unpaired t-test, and mean differences with a P value of ≤ 0.01 were considered significant. ns, not significant. (D, E) Promoter activity of the transcriptional fusions PctxA-lux (D), and PtcpA-lux (E) were measured from cells grown to exponential phase in the indicated strains. Individual data points (circles–RvvA present; triangles–RvvA deleted) of Relative Luminescent Units (RLU) are displayed on top of a boxplot for each strain.