Table 1. Interaction associations of pairs that reached p≤5.86e-10 in the final combined meta-analysis.

Replication and final combined results indicate the meta-analyzed Z scores. See S4 Table for all pairs that were significant at any stage.

Trait & Expression Tissue Gene Name, ENSGID, chromosome and midpoint bp location			Discovery			Replication		Final Combined
Gene 1	Gene 2	Expression ρ	β	SE	p	Z	p	Z	p	Direction
pAUDIT, Prefrontal Cortex Expression
PRKCG (ENSG00000126583, 19:54296675)	WNT6 (ENSG00000115596, 2:219731750)	0.000	0.068	0.011	2.86E-10	1.884	0.060	6.483	9.01E-11	+++
PRKCG (ENSG00000126583, 19:54296675)	MAP7 (ENSG00000135525, 6:136767916)	-8.39E-05	0.040	0.006	1.51E-10	2.432	0.015	6.816	9.36E-12	+++
CENPN (ENSG00000166451, 2:122008473)	TFCP2L1 (ENSG00000115112, 16:81053411)	0.003	-0.157	0.022	4.14E-13	-1.535	0.125	-7.171	7.43E-13	-+-
PRKCG (ENSG00000126583, 19:54296675)	SEZ6L2 (ENSG00000174938, 16:29896674)	-0.002	0.105	0.017	1.89E-10	1.82	0.069	6.511	7.45E-11	+++
GAD, Cross-Tissue Expression, sCCA3
MTMR10 (ENSG00000166912, 15: 30965284)	SEPHS1 (ENSG00000086475, 10: 13332863)	0.0004	0.0123	0.002	5.79E-09	6.359	2.03E-10	6.359	2.03E-10	+++