Skip to main content

. 1954 Aug;7(3):201–208. doi: 10.1136/jcp.7.3.201

A Family Illustrating the Double Inheritance of the Sickle Cell Trait and of Mediterranean Anaemia

J G Humble ^1,^2,^3,⁴, Ian Anderson ^1,^2,^3,⁴, J C White ^1,^2,^3,⁴, Tristram Freeman ^1,^2,^3,⁴

PMCID: PMC1023792 PMID: 13192194

201

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

BEAVEN G. H., WHITE J. C. Detection of foetal and sickle-cell haemoglobins in human anaemias. Nature. 1953 Nov 28;172(4387):1006–1006. doi: 10.1038/1721006a0. [DOI] [PubMed] [Google Scholar]
CAMINOPETROS J. The sickle-cell anomaly as a sign of Mediterranean anemia. Lancet. 1952 Apr 5;1(6710):687–692. doi: 10.1016/s0140-6736(52)90451-0. [DOI] [PubMed] [Google Scholar]
FLYNN F. V., DE MAYO P. Microelectrophoresis of protein on filter-paper. Lancet. 1951 Aug 11;2(6676):235–239. doi: 10.1016/s0140-6736(51)93239-4. [DOI] [PubMed] [Google Scholar]
Humble J. G. A Simplified Price-Jones Technique. J Clin Pathol. 1948 Feb;1(2):77–79. [PMC free article] [PubMed] [Google Scholar]
Itano H. A. A Third Abnormal Hemoglobin Associated with Hereditary Hemolytic Anemia. Proc Natl Acad Sci U S A. 1951 Dec;37(12):775–784. doi: 10.1073/pnas.37.12.775. [DOI] [PMC free article] [PubMed] [Google Scholar]
KAPLAN E., ZUELZER W. W., NEEL J. V. A new inherited abnormality of hemoglobin and its interaction with sickle cell hemoglobin. Blood. 1951 Dec;6(12):1240–1249. [PubMed] [Google Scholar]
LIQUORI A. M. Presence of Foetal Haemoglobin in Cooley's anaemia. Nature. 1951 Jun 9;167(4258):950–951. doi: 10.1038/167950b0. [DOI] [PubMed] [Google Scholar]
NEEL J. V., ITANO H. A., LAWRENCE J. S. Two cases of sickle cell disease presumably due to the combination of the genes for thalassemia and sickle cell hemoglobin. Blood. 1953 May;8(5):434–443. [PubMed] [Google Scholar]
PAULING L., ITANO H. A. Sickle cell anemia a molecular disease. Science. 1949 Nov 25;110(2865):543–548. doi: 10.1126/science.110.2865.543. [DOI] [PubMed] [Google Scholar]
PERUTZ M. F., MITCHISON J. M. State of haemoglobin in sickle-cell anaemia. Nature. 1950 Oct 21;166(4225):677–679. doi: 10.1038/166677a0. [DOI] [PubMed] [Google Scholar]
PERUTZ R. R., LIQUORI A. M., EIRICH F. X-ray and solubility studies of the haemoglobin of sickle-cell anaemia patients. Nature. 1951 Jun 9;167(4258):929–931. doi: 10.1038/167929a0. [DOI] [PubMed] [Google Scholar]
POWELL W. N., RODARTE J. G., NEEL J. V. The occurrence in a family of Sicilian ancestry of the traits for both sickling and thalassemia. Blood. 1950 Oct;5(10):887–897. [PubMed] [Google Scholar]
SILVESTRONI E., BIANCO I. Genetic aspects of sickle cell anemia and microdrepanocytic disease. Blood. 1952 Apr;7(4):429–435. [PubMed] [Google Scholar]
SINGER K., CHERNOFF A. I., SINGER L. Studies on abnormal hemoglobins. I. Their demonstration in sickle cell anemia and other hematologic disorders by means of alkali denaturation. Blood. 1951 May;6(5):413–428. [PubMed] [Google Scholar]
SINGER K., FISHER B. Studies on abnormal hemoglobins. VI. Electrophoretic demonstration of type S (sickle cell) hemoglobin in erythrocytes incapable of showing the sickle cell phenomenon. Blood. 1953 Mar;8(3):270–275. [PubMed] [Google Scholar]
STURGEON P., ITANO H. A., VALENTINE W. N. Chronic hemolytic anemia associated with thalassemia and sickling traits. Blood. 1952 Mar;7(3):350–357. [PubMed] [Google Scholar]

ACTIONS

RESOURCES