Table 5.
Percent of patients achieving decrease of diastolic blood pressure for 5 mm Hg or more (from the baseline) at each study visit (both at office and home measurements).
| Visit | Row legend | No antihypertensive added | First-line AH drug added | Spironolactone added | Central antihypertensive added | Spironolactone + central antihypertensive added | Null hypothesis probability |
|---|---|---|---|---|---|---|---|
| 1 | No of patients with added antihypertensive at previous visit | 387 | 61 | 60 | 7 | 0 | 0.680 |
| Percent of responders | 39.00% | 32.80% | 43.30% | 42.90% | 0.00% | ||
| 2 | No of patients with added antihypertensive at previous visit | 49 | 29 | 417 | 15 | 5 | 0.014* |
| Percent of responders | 44.90% | 58.60% | 66.90% | 66.70% | 100% | ||
| 3 | No of patients with added antihypertensive at previous visit | 26 | 21 | 447 | 14 | 7 | 0.681 |
| Percent of responders | 65.40% | 81.00% | 77.40% | 78.60% | 85.7% | ||
| 4 | No of patients with added antihypertensive at previous visit | 19 | 16 | 457 | 12 | 11 | 0.022* |
| Percent of responders | 63.20% | 75.00% | 84.20% | 66.70% | 100% | ||
| 5 | No of patients with added antihypertensive at previous visit | 14 | 16 | 459 | 13 | 13 | 0.060 |
| Percent of responders | 100% | 81.30% | 86.30% | 61.50% | 92.30% | ||
| 6 | No of patients with added antihypertensive at previous visit | 13 | 16 | 460 | 10 | 16 | 0.161 |
| Percent of responders | 84.60% | 75.00% | 88.00% | 70.00% | 86.70% |
*
Significant difference.