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. 2023 Jun 2;13:8947. doi: 10.1038/s41598-023-34634-6

Table 3.

Generalized linear model for z-score in Argentinian and German children with cerebral palsy according to different growth charts (n = 799).

Model Anthropometric measurement Variables β 95%CI p
(a) WHO charts, 2007
 Main effect model z-score BMI-for-age Argentina, non-oral feeding, GMFCS IV and V Reference
Germany 0.041 − 0.22 to 0.30 0.048
Oral Feeding − 0.440 − 0.90 to 0.02 0.063
GMFCS I to III 1.105 0.84 to 1.37  < 0.001
Age − 0.037 − 0.06 to − 0.01 0.007
 Interaction effect model z-score BMI-for-age GMFCS IV and V *age − 0.102 − 0.13 to − 0.07  < 0.001
 Main effect model z-score Height-for-age Argentina, non-oral feeding, GMFCS IV and V Reference
Germany 0.852 0.62 to 1.08  < 0.001
Oral Feeding − 0.16 0.21 to − 0.57 0.451
GMFCS I to III 1.338 1.10 to 1.58  < 0.001
Age − 0.061 − 0.08 to − 0.37  < 0.001
 Interaction effect model z-score Height-for-age Germany*age − 0.073 − 0.13 to − 0.10 0.006
Argentina*age − 0.144 − 0.18 to − 0.10  < 0.001
GMFCS I to III*age 0.087 0.04 to 0.14 0.001
Germany* GMFCS I to III 0.767 0.17 to 1.36 0.012
Germany* GMFCS IV andV 0.233 − 0.34 to 0.81 0.428
Argentina* GMFCS I to III 0.525 − 0.06 to 1.11 0.080
(b) US CP chart (2011)
 Main effect model z-score BMI-for-age Argentina, non-oral feeding, GMFCS IV and V Reference
Germany − 0.026 − 0.15 to 0.10 0.685
Oral Feeding − 0.306 − 0.53 to − 0.81 0.008
GMFCS I to III 0.148 0.02 to 0.28 0.025
Age 0.044 0.03 to 0.06  < 0.001
 Interaction effect model z-score BMI-for-age Oral Feeding*age 0.042 0.03 to 0.05  < 0.001
Non-Oral Feeding*age 0.062 0.04 to 0.08  < 0.001
 Main effect model z-score Height-for-age Argentina, non-oral feeding, GMFCS IV and V Reference
Germany 0.321 0.21 to 0.44  < 0.001
Oral Feeding − 0.222 − 0.43 to − 0.02 0.034
GMFCS I to III 0.096 − 0.02 to 0.21 0.116
Age − 0.050 − 0.06 to − 0.04  < 0.001
 Interaction  effect model z-score Height-for-age Germany*age − 0.032 − 0.05 to − 0.02  < 0.001
Argentina*age − 0.066 − 0.08 to − 0.05  < 0.001
 Main effect model z-score Weight-for-age Argentina, non-oral feeding, GMFCS IV and V Reference
Germany 0.198 0.05 to 0.34 0.007
Oral Feeding − 0.429 − 0.69 to − 0.17 0.001
GMFCS I to III 0.120 − 0.03 to 0.00 0.115
age − 0.013 0.85 to 1.04 0.089
 Interaction effect model z-score Weight-for-age Germany*Oral feeding − 0.261 − 0.57 to 0.04 0.095
Argentina* Oral Feeding − 0.553 − 0.86 to − 0.24  < 0.001

Significant differences are marked in bold.

GMFCS gross motor function classification system.