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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Mol Cancer Res. 2023 Jun 1;21(6):511–524. doi: 10.1158/1541-7786.MCR-22-1008

Table 4. Dysregulated microRNAs in other Soft Tissue Sarcomas.

Tables reporting the most relevant microRNAs found differentially expressed in several different histological types of Soft Tissue Sarcoma (excluding liposarcoma) with their target genes.

microRNA Expression Target STS type Reference
miR-1 DOWN CCND2, PAX3 RMS Li L, et al. Lab. Investig. 2012.
miR-143 DOWN PRC1, PLK1, BCL2 SS Subramanian S, et al. Oncogene. 2008.
miR-152 DOWN MET, KIT LMS Pazzaglia L, et al. Cell. Oncol. 2017.
miR-199b-5p DOWN
UP
- LMS
UPS
Guled M, et al. Genes Chromosom. Cancer. 2014.
miR-206 DOWN CCND2, PAX3, PAX7, MET, NOTCH3 RMS Li L, et al. Lab. Investig. 2012.
Taulli R, et al. JCI. 2009.
Missiaglia E, et al. Br J Cancer. 2010.
Hanna J.A, et al Cell Death & Disease. 2016.
miR-221 DOWN CCND2, CDK6, ERBB3 RMS Hanna J.A, et al. Oncogene. 2018.
miR-29 DOWN CCND2, PAX3, E2F7, MMP2 FS
RMS
Kim J.H, et al. Chonnam Med. J. 2017.
miR-29c DOWN MMP2 MPNST Presneau N, et al. Br J Cancer. 2013.
miR-30d DOWN KPNB1 MPNST Zhang P, et al. J. Pathol. 2014.
miR-340 DOWN SIRT7 AS Wang X, et al. Biomed Pharmacother. 2018.
miR-34a DOWN - MPNST Subramanian S, et al. J. Pathol. 2010.
miR-378a-3p DOWN IGF1R RMS Megiorni F, et al. BMC Cancer. 2014.
miR-497-5p DOWN KCa3.1 AS Chen Y, et al. Oncotarget. 2016.
miR-17 UP CDKN1A SS Minami Y, et al. Cancer Sci. 2014.
miR-183 UP EGR1, PTEN RMS
SS
Sarver A.L. et al. Cancer Res. 2010.
miR-21 UP PDCD4 MPNST Itani S, et al. J Cancer Res Clin Oncol. 2012.
miR-27a UP RARA, RXRA RMS Tombolan L, et al. PLoS ONE. 2015.
miR-320a UP
DOWN
- LMS
UPS
Guled M, et al. Genes Chromosom. Cancer. 2014.
miR-373 UP SIRT1, mTOR FS Liu P, et al. J. Cell Physiol. 2012.
miR-486-5p UP - RMS Hanna J.A, et al. Oncogene. 2018.
miR-520c UP SIRT1, mTOR FS Liu P, et al. J. Cell Physiol. 2012.
miR-9-5p UP - RMS Missiaglia E, et al. Cancer Letters. 2017.