Table 2.
Univariate and Multivariable Cox Proportional Model for Overall Survival
Univariate HR (95% CI) | p-value1 | Multivariable HR (95% CI) | p value | |
---|---|---|---|---|
Age | 1.03 | <0.001 | 1.02 | 0.03 |
(1.02 - 1.05) | (1.00 - 1.04) | |||
Sex | ||||
Female vs. Male | 0.7 | 0.02 | 0.75 | 0.07 |
(0.51 - 0.95) | (0.55 - 1.03) | |||
Charlson Deyo Score | ||||
1 or 2 vs. 0 | 1.45 | 0.02 | 1.45 | 0.02 |
(1.06 - 1.99) | (1.05 - 2.02) | |||
Insurance | ||||
Government vs. Private Insurance | 1.4 | 0.03 | ||
(1.02 - 1.91) | ||||
No insurance/unknown vs. Private Insurance | 1.01 | 0.9 | ||
(0.54 - 1.91) | ||||
Pathologic Stage - N | ||||
N1 vs. N0 | 1.55 | 0.009 | 1.48 | 0.02 |
(1.12 - 2.16) | (1.05 - 2.08) | |||
Histology | ||||
Adenocarcinoma vs. Squamous Cell Carcinoma | 0.57 | 0.01 | 0.59 | 0.02 |
(0.37 - 0.88) | (0.38 - 0.92) | |||
Others vs. Squamous Cell Carcinoma | 0.65 | 0.09 | 0.65 | 0.1 |
(0.39 - 1.09) | (0.39 - 1.10) | |||
Surgery | ||||
Pneumonectomy vs. Lobectomy | 1.52 | 0.1 | ||
(0.82 - 2.8) | ||||
Surgical Approach | ||||
Thoracotomy vs.VATS | 1.2 | 0.3 | ||
(0.78 - 1.85) | ||||
Radiation | ||||
Yes vs. No | 0.89 | 0.6 | ||
(0.58 - 1.37) | ||||
Chemotherapy | ||||
Yes vs. No | 0.71 | 0.04 | 0.66 | 0.01 |
(0.52 - 0.99) | (0.47 - 0.92) |
Multivariable cox modeling was performed using patient age, sex, Charlson Deyo score, insurance type, tumor histology and pathologic N stage, surgery type, radiation therapy status, and adjuvant chemotherapy as covariates. All statistically significant variables (P < 0.05) are highlighted in bold.
Wald p