Table 3.
Diagnostic Accuracy of Eight New Sex-Specific Cut-Off Scores of the ASRS-18 Among Psychiatrically Referred Adolescents.
| ASRS-18 | Base rate% | AUC (95% CI) | Sens.% | Spec.% | Accuracy% | PPV | NPV | LR+ (95% CI) | LR– (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
| Girls (n = 67) | 40.30 | .80⁎⁎⁎ (0.69–0.92) | |||||||
| Screening cut off (≥25 points)a | 92.59 | 35.00 | 58.20 | 49.01 | 87.50 | 1.42(1.11–1.83) | 0.21(0.05–0.86) | ||
| Diagnostic cut off (≥43 points)b | 55.56 | 90.00 | 72.12 | 78.94 | 75.01 | 5.56(2.07–14.94) | 0.49(0.32–0.76) | ||
| Balanced screening cut off (≥30 points)c | 81.50 | 50.00 | 62.68 | 52.37 | 80.01 | 1.63 (1.14–2.33) | 0.37(0.16–0.87) | ||
| Balanced diagnostic cut off (≥44 points)d | 51.90 | 92.50 | 76.12 | 82.35 | 74.01 | 6.91(2.19–21.78) | 0.52(0.35–0.78) | ||
| Boys (n = 44) | 68.18 | .71⁎⁎ (0.53–0.89) | |||||||
| Screening cut off (≥24 points)a | 90.00 | 42.86 | 75.00 | 77.14 | 66.67 | 1.58(0.99–2.52) | 0.23(0.07–0.80) | ||
| Diagnostic cut off (≥45 points)b | 16.67 | 92.86 | 40.91 | 83.33 | 34.21 | 2.33(0.30–18.15) | 0.90(0.72–1.11) | ||
| Balanced screening cut off (≥26 points)c | 83.30 | 57.10 | 75.00 | 80.64 | 61.54 | 1.94 (1.04–3.64) | 0.29(0.12–0.73) | ||
| Balanced diagnostic cut off (≥38 points)d | 56.70 | 71.40 | 61.63 | 80.95 | 43.48 | 1.98(0.82–4.80) | 0.61(0.36–1.03) |
a
cut off with minimum 90% sensitivity.
b
cut off with minimum 90% specificity.
c
cut off with maximized sensitivity at minimum 50% specificity.
d
cut off with maximized specificity at minimum 50% sensitivity.
⁎⁎
p < .01.
⁎⁎⁎
p < .001.
Note: ASRS-18: The World Health Organization ADHD Self-Report Scale, 18 items; Base rate: rate of adolescents with a diagnosis of ADHD/ADD; AUC: area under the curve; Sens: Sensitivity; Spec: Specificity; Accuracy: correctly classified; PPV: Positive Predictive Value; NPV: Negative Predictive Value; LR+: Positive Likelihood Ratio; LR–: Negative Likelihood Ratio.