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. 2023 Apr 20;38:103414. doi: 10.1016/j.nicl.2023.103414

Table 4.

Connectivity patterns associated with pain phenotypes and severity.

Pain Phenotype and Severity Connectivity Pattern Alterations
↑ Neuropathic pain intensity ↓ Intralimbic and limbostriatal
↑ Nociceptive pain intensity ↓ Thalamocortical and Thalamolimbic
↑ Neuropathic + nociceptive pain intensities ↑ and ↓ Limbocortical
(↓ pPaHC – parietal; ↑ amygdala - parietal)
Neuropathic > nociceptive pain intensity ↓ Limbocortical
Neuropathic < nociceptive pain intensity ↑ Limbocortical

Summary of connectivity pattern alterations associated with pain phenotypes and severity. Full results and specific regions can be found in Table 3. Posterior parahippocampal gyrus (pPaHC).