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. 2023 May 29;17:58–69. doi: 10.33393/dti.2022.2595

Table I -.

Hubs identified as potential targets from among the downregulated genes in Panchvalkal-exposed Pseudomonas aeruginosa

No. Gene ID Gene name Functional role
1 PA0520 nirQ Denitrification regulatory protein NirQ
2 PA0519 nirS Heme d1 biosynthesis protein, which is important for denitrification (20)
3 PA0524 norB Nitric oxide reductase subunit B
4 PA0523 norC Nitric oxide reductase subunit C
5 PA0525 NorD Nitric oxide reductase NorD protein
6 PA0521 NorE Nitric oxide reductase NorE protein
7 PA3395 nosY Nitrous oxide reductase; a Cu-processing system permease protein having role in denitrification pathway (21)
8 PA3396 nosL A lipoprotein attached to the outer membrane described as a copper-binding protein. Regulator of nos operon, NosR also associates with NosL. This protein is probably responsible for the insertion and coordination of the multicopper center within NosZ (22).