Table 1. Baseline Patient and Hospital Characteristics of the Improve Acute Reperfusion Treatment Quality for Stroke in China (IMPROVE Stroke Care in China) Triala.
| Characteristic | Intervention (n = 5689 [46.9%]) | Control (n = 6443 [53.1%]) | Difference (95% CI) |
|---|---|---|---|
| Patient characteristics | |||
| Demographic characteristics | |||
| Age, mean (SD), y | 66.4 (12.1) | 65.9 (12.0) | 0.5 (0.1 to 0.9) |
| Sex | |||
| Male | 3655 (64.2) | 4104 (63.7) | 0.5 (−1.2 to 2.3) |
| Female | 2034 (35.8) | 2339 (36.3) | −0.5 (−2.3 to 1.2) |
| BMI, mean (SD) | 23.6 (3.5) | 23.9 (4.0) | −0.3 (−0.4 to −0.2) |
| NIHSS score at admission, median (IQR) | 5.0 (2.0 to 10.0) | 5.0 (2.0 to 10.0) | 0.0 (0.0 to 0.0) |
| Current smoking | 1570 (27.6) | 1668 (25.9) | 1.7 (0.1 to 3.3) |
| Drinking | 1386 (24.4) | 1607 (24.9) | −0.5 (−2.1 to 1.0) |
| Medical history | |||
| Stroke or TIA | 1358 (23.9) | 2087 (32.4) | −8.5 (−10.1 to −6.9) |
| Hypertension | 3435 (60.4) | 4022 (62.4) | −2.0 (−3.8 to −0.3) |
| Diabetes | 1092 (19.2) | 1309 (20.3) | −1.1 (−2.5 to −0.3) |
| Dyslipidemia | 301 (5.3) | 424 (6.6) | −1.3 (−2.1 to −0.5) |
| Myocardial infarction | 117 (2.1) | 125 (1.9) | 0.2 (−0.4 to 0.6) |
| Atrial fibrillation | 579 (10.2) | 528 (8.2) | 2.0 (1.0 to 3.0) |
| Peripheral vascular disease | 52 (0.9) | 113 (1.8) | −0.9 (−1.2 to −0.4) |
| Medication history | |||
| Antiplatelet agent | 904 (15.9) | 1346 (20.9) | −5.0 (−6.4 to −3.6) |
| Anticoagulant drugs | 182 (3.2) | 370 (5.7) | −2.5 (−3.3 to −1.8) |
| Antihypertensive drugs | 2501 (44.0) | 2876 (44.6) | −0.6 (−2.4 to 1.1) |
| Antidiabetics | 853 (15.0) | 1051 (16.3) | −1.3 (−2.6 to 0.0) |
| Statins | 749 (13.2) | 1212 (18.8) | −5.6 (−6.9 to −4.3) |
| Onset-to-door time, median (IQR), min | 95.0 (55.0 to 144.0) | 94.0 (54.0 to 146.0) | −2.0 (−4.0 to 0.0) |
| Hospital characteristics | |||
| Hospital level | |||
| Tertiary | 3819 (67.1) | 4241 (65.8) | 1.3 (−0.4 to 3.0) |
| Secondary | 1870 (32.9) | 2202 (34.2) | −1.3 (−3.0 to 0.4) |
| Hospital location | |||
| Eastern | 2385 (41.9) | 3189 (49.5) | −7.6 (−9.3 to −5.8) |
| Central | 1857 (32.6) | 1807 (28.0) | 4.6 (3.0 to 6.2) |
| Western | 1447 (25.4) | 1447 (22.5) | 2.9 (1.5 to 4.5) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); NIHSS, National Institutes of Health Stroke Scale; TIA, transient ischemic attack.
a
Data are presented as number (percentage) unless otherwise indicated.