. 2023 Apr 18;3(4):100314. doi: 10.1016/j.xops.2023.100314

Table 5.

Multivariable ORs of RRDs or RTs after Cataract Surgery by Ocular Comorbidity and Cataract Surgery Complexity

Comorbidities and Cataract Surgery Complexity Indicators
Condition	Present Before Cataract Procedure	Cataract Procedures	Retinal Events (RRD or RT)				RRD				RT
Condition	Present Before Cataract Procedure	Cataract Procedures	Uni OR (95% CI)^∗	P Value	Multi-OR (95% CI)^†	P Value	Uni OR (95% CI)^∗	P Value	Multi-OR (95% CI)^†	P Value	Uni OR (95% CI)^∗	P Value	Multi-OR (95% CI)^†	P Value
Lattice degeneration	No	3 139 456	31.22 (29.91–32.59)	< 0.001	23.14 (22.13–24.2)	< 0.001	15.92 (14.89–17.02)	< 0.001	10.53 (9.82–11.28)	< 0.001	54.48 (51.55–57.59)	< 0.001	43.86 (41.39–46.49)	< 0.001
Lattice degeneration	Yes	37 739	31.22 (29.91–32.59)	< 0.001	23.14 (22.13–24.2)	< 0.001	15.92 (14.89–17.02)	< 0.001	10.53 (9.82–11.28)	< 0.001	54.48 (51.55–57.59)	< 0.001	43.86 (41.39–46.49)	< 0.001
High myopia	No	2 519 634	1.49 (1.44–1.56)	< 0.001	1.12 (1.08–1.17)	< 0.001	1.51 (1.43–1.59)	< 0.001	1.2 (1.14–1.27)	< 0.001	1.51 (1.43–1.6)	< 0.001	1.06 (1–1.12)	0.07
High myopia	Yes	657 561	1.49 (1.44–1.56)	< 0.001	1.12 (1.08–1.17)	< 0.001	1.51 (1.43–1.59)	< 0.001	1.2 (1.14–1.27)	< 0.001	1.51 (1.43–1.6)	< 0.001	1.06 (1–1.12)	0.07
Posterior vitreous detachment	No	2 845 917	1.27 (1.2–1.34)	< 0.001	1.13 (1.07–1.2)	< 0.001	1.2 (1.12–1.29)	< 0.001	1.24 (1.15–1.34)	< 0.001	1.35 (1.25–1.46)	< 0.001	1.01 (0.93–1.09)	0.81
Posterior vitreous detachment	Yes	331 278	1.27 (1.2–1.34)	< 0.001	1.13 (1.07–1.2)	< 0.001	1.2 (1.12–1.29)	< 0.001	1.24 (1.15–1.34)	< 0.001	1.35 (1.25–1.46)	< 0.001	1.01 (0.93–1.09)	0.81
Hypermature cataract	No	3 172 635	1.98 (1.4–2.79)	< 0.001	1.61 (1.13–2.28)	0.01	2.41 (1.6–3.63)	< 0.001	1.61 (1.06–2.45)	0.03	1.4 (0.77–2.53)	0.27	1.46 (0.8–2.67)	0.22
Hypermature cataract	Yes	4560	1.98 (1.4–2.79)	< 0.001	1.61 (1.13–2.28)	0.01	2.41 (1.6–3.63)	< 0.001	1.61 (1.06–2.45)	0.03	1.4 (0.77–2.53)	0.27	1.46 (0.8–2.67)	0.22
Pseudoexfoliation	No	3 067 803	1 (0.9–1.1)	0.96	1.03 (0.93–1.14)	0.57	1 (0.88–-1.14)	0.96	0.98 (0.86–1.12)	0.77	0.99 (0.86–1.15)	0.94	1.11 (0.96–1.29)	0.17
Pseudoexfoliation	Yes	109 392	1 (0.9–1.1)	0.96	1.03 (0.93–1.14)	0.57	1 (0.88–-1.14)	0.96	0.98 (0.86–1.12)	0.77	0.99 (0.86–1.15)	0.94	1.11 (0.96–1.29)	0.17
Floppy iris syndrome	No	3 155 198	1.01 (0.82–1.26)	0.90	0.82 (0.66–1.03)	0.08	1.1 (0.84–1.45)	0.49	0.77 (0.58–1.02)	0.06	0.84 (0.59–1.19)	0.33	0.88 (0.62–1.26)	0.49
Floppy iris syndrome	Yes	21 997	1.01 (0.82–1.26)	0.90	0.82 (0.66–1.03)	0.08	1.1 (0.84–1.45)	0.49	0.77 (0.58–1.02)	0.06	0.84 (0.59–1.19)	0.33	0.88 (0.62–1.26)	0.49
Use of complex cataract surgery CPT Code (66982)	No	2 975 930	1.25 (1.17–1.34)	< 0.001	1.27 (1.19–1.37)	< 0.001	1.59 (1.47–1.72)	< 0.001	1.52 (1.4–1.66)	< 0.001	0.82 (0.73–0.92)	0.001	0.89 (0.79–1.01)	0.07
Use of complex cataract surgery CPT Code (66982)	Yes	201 265	1.25 (1.17–1.34)	< 0.001	1.27 (1.19–1.37)	< 0.001	1.59 (1.47–1.72)	< 0.001	1.52 (1.4–1.66)	< 0.001	0.82 (0.73–0.92)	0.001	0.89 (0.79–1.01)	0.07

CI = confidence interval; CPT = Current Procedural Terminology; IR = incidence rate; OR = odds ratio; (Ref) = reference; RRD = rhegmatogenous retinal detachment; RT = retinal tear.

Bold OR (95% CI) values indicate statistical significance (P < 0.05).

^∗

Univariable ORs are based on coefficients from a logistic regression model of the single variable.

^†

Multivariable ORs are based on coefficients from a multivariable logistic regression model containing all of the demographic factors (age at cataract surgery, sex, race, ethnicity, indicator for the presence of bilateral cataract surgeries), comorbidities (lattice degeneration, high myopia, posterior vitreous detachment), and factors associated with cataract surgery complexity (hypermature cataract, pseudoexfoliation, floppy iris syndrome, and complex cataract surgery CPT code). Analyses adjusted for intereye correlation yielded similar results.