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. 2023 Apr;228(4):418–429.e34. doi: 10.1016/j.ajog.2022.10.004

Table S17.

Pooled relative risk and mean likelihood ratios for NICU admission, according to BP cut-offs at <20 weeks, determined by ACC/AHA BP categories

COMPARATOR
BP measured at <20 weeks Ref RR [95% CI] I2, (95% PI) -LR +LR
Diagnostic threshold: sBP 120mmHg (with dBP <80mmHg)
Pooled Normal (<120/80 mmHg) 1.5 [1.2, 1.8] I2=45%, (0.2, 10.15) 0.87 [0.82, 0.92] 1.36 [1.21, 1.52]
Greenberg 1.3 [1.3, 1.4] 0.90 [0.87, 0.92] 1.27 [1.20, 1.35]
Reddy 1.6 [1.2, 2.1] 0.87 [0.78, 0.96 1.38 [1.15, 1.86]
Rosner 2.1 [1.2, 3.5] 0.73 [0.55, 0.96] 1.70 [1.20, 2.39]
Diagnostic threshold: sBP 130mmHg or dBP 80mmHg
Pooled Normal + ElevatedBP (<130/80 mmHg) 1.4 [1.2, 1.7] I2=96%, (1.1, 1.8) 0.92 [0.86, 0.97] 1.39 [1.11, 1.72]
Bello 1.7 [1.6, 1.7] 0.89 [0.88, 0.90] 1.56 [1.50, 1.62]
Darwin 2.2 [1.8, 2.7] 0.78 [0.72, 0.85] 1.97 [1.66, 2.32]
Duffy 1.2 [1.1, 1.3] 0.96 [0.94, 0.98] 1.14 [1.08, 1.19]
Greenberg 1.4 [1.3, 1.6] 0.93 [0.92, 0.95] 1.43 [1.31, 1.56]
Reddy 1.7 [1.2, 2.3] 0.91 [0.85, 0.98] 1.55 [1.18, 2.03]
Sabol 0.9 [0.8, 1.1] 1.03 [0.98, 1.07] 0.91 [0.76, 1.09]
Diagnostic threshold: sBP 140mmHg or dBP 90mmHg
Pooled Normal + Elevated BP + Stage 1 HTN (<140/90 mmHg) 1.8 [1.3, 2.4] I2=93%, (0.4, 9.0) 0.95 [0.91, 0.99] 1.98 [1.18, 3.15]
Bello 2.0 [1.9, 2.1] 0.95 [0.94, 0.96] 2.06 [1.92, 2.20]
Darwin 2.4 [1.9, 3.0] 0.84 [0.79, 0.90] 2.40 [1.92, 2.99]
Greenberg 1.5 [1.4, 1.7] 0.96 [0.95, 0.97] 1.62 [1.43, 1.85]
Reddy 4.1 [2.3, 7.4] 0.96 [0.93, 0.99] 4.11 [2.28, 7.43]
Rosner 2.0 [0.9, 4.5] 0.94 [0.85, 1.04] 2.14 [0.82, 5.58]
Sabol 0.7 [0.6, 1.0] 1.04 [1.01, 1.07] 0.71 [0.53, 0.96]

ACC (American College of Cardiology), AHA (American Heart Association), BP (blood pressure), dBP (diastolic BP), -LR (negative likelihood ratio), +LR (positive likelihood ratio), NICU (neonatal intensive care unit), sBP (systolic BP), CI (confidence interval), PI (prediction interval)

Slade. The diagnostic accuracy of American College of Cardiology-American Heart Association blood pressure categories for identification of women and babies at risk. Am J Obstet Gynecol 2023.