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. 2023 Apr;228(4):418–429.e34. doi: 10.1016/j.ajog.2022.10.004

Table S19.

Pooled relative risk and mean likelihood ratios for eclampsia, according to BP cut-offs at <20 weeks, determined by ACC/AHA BP categories

COMPARATOR
BP measured at <20 weeks Ref RR [95% CI] I2, (95% PI) -LR +LR
Diagnostic threshold: sBP 120mmHg (with dBP <80mmHg)
Pooled Normal (<120/80 mmHg) 2.2 [0.8, 6.5] I2=40%, (UTD) 0.87 [0.62, 1.00] 1.73 [0.97, 2.60]
Bellad 0.5 [0.1, 3.7] 1.01 [0.95, 1.08] 0.76 [0.16, 3.64]
Greenberg 2.7 [1.3, 5.5] 0.68 [0.47, 0.97] 1.82 [1.30, 2.55]
Qureshi 5.7 [0.8, 40.6] 0.59 [0.24, 1.41] 3.36 [1.40,8.09]
Sevene - 0.57 [0.08, 4.05] 4.07 [0.57, 29.11]
Diagnostic threshold: sBP 130mmHg or dBP 80mmHg
Pooled Normal + Elevated BP(<130/80 mmHg) 2.5 [1.1, 5.4] I2=66%, (0.1, 48.6) 0.84 [0.67, 0.96] 2.57 [1.39, 4.32]
Bellad 0.9 [0.1, 6.7] 0.99 [0.93, 1.06] 1.35 [0.28, 6.51]
Duffy 1.5 [1.2, 5.4] 0.89 [0.81, 0.97] 1.37 [1.13, 1.65]
Greenberg 3.8 [1.9, 7.9] 0.71 [0.54, 0.94] 2.76 [1.79, 4.27]
Qureshi 10.2 [1.4, 72.2] 0.55 [0.23, 1.32] 5.60 [2.32, 13.50]
Sevene - 0.53 [0.08, 3.79] 7.75 [1.07, 55.88]
Diagnostic threshold: sBP 140mmHg or dBP 90mmHg
Pooled Normal + Elevated BP + Stage 1 HTN (<140/90 mmHg) 7.3 [3.8, 14.3] I2=0% (0.1, 560.9) 0.87 [0.69, 0.96] 7.79 [4.16, 13.30]
Bellad 5.2 [0.7, 37.6] 0.96 [0.90, 1.03] 7.50 [1.53, 36.65]
Greenberg 7.5 [3.6, 15.7] 0.69 [0.53, 0.89] 5.31 [3.34, 8.64]
Qureshi 10.0 [0.5, 183.7] 0.91 [0.68, 1.22] 9.07 [0.65, 126.89]
Sevene - 0.51 [0.07, 3.62] 24.08 [3.22, 179.93]

ACC (American College of Cardiology), AHA (American Heart Association), BP (blood pressure), dBP (diastolic BP), -LR- (negative likelihood ratio), +LR (positive likelihood ratio), sBP (systolic BP), UTD (unable to determine), CI (confidence interval), PI (prediction interval)

Slade. The diagnostic accuracy of American College of Cardiology-American Heart Association blood pressure categories for identification of women and babies at risk. Am J Obstet Gynecol 2023.