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. 2023 Apr;228(4):418–429.e34. doi: 10.1016/j.ajog.2022.10.004

Table S21.

Pooled relative risk and mean likelihood ratios for stroke, according to BP cut-offs at <20 weeks, determined by ACC/AHA BP categories

COMPARATOR
BP measured at <20 weeks Ref RR [95% CI] I2, (95% PI) -LR +LR
Diagnostic threshold: sBP 120mmHg (with dBP <80mmHg)
Pooled Normal (<120/80 mmHg) 2.1 [0.7, 6.2], I2= 63% (UTD) 0.89 [0.65, 1.03] 2.08 [0.74, 4.39]
Bellad 3.5 [1.0, 12.2] 0.88 [0.72, 1.08] 3.13[1.11, 8.81]
Qureshi 3.4 [1.5, 7.8] 0.73 [0.54, 1.00] 2.52 [1.50, 4.23]
Sevene 0.6 [0.1, 2.4] 1.05 [0.95, 1.17] 0.59 [0.15, 2.28]
Diagnostic threshold: sBP 130mmHg or dBP 80mmHg
Pooled Normal + ElevatedBP (<130/80mmHg) 2.1 [0.8, 5.6] I2=76%, (0.0, 105.9) 0.86 [0.84, 0.91] 2.8 [1.4, 5.2]
Bellad 6.5 [1.9, 22.2] 0.84 [0.68, 1.04] 6.18 [2.39, 16.01]
Duffy 1.3 [1.1, 1.4] 0.94 [0.91, 0.97] 1.19 [1.09, 1.29]
Qureshi 3.4 [1.4, 8.5] 0.81 [0.64, 1.02] 2.93 [1.50, 5.69]
Sevene 0.3 [0.0, 4.3] 1.05 [1.00, 1.10] 0.27 [0.02, 4.21]
Diagnostic threshold: sBP 140mmHg or dBP 90mmHg
Pooled Normal + Elevated BP +Stage 1 HTN (<140/90 mmHg) 8.6 [1.5, 50.2] I2=70%, (UTD) 0.90 [0.77, 0.98] 12.7 [2.11, 41.10]
Bellad 22.8 [5.4, 97.3] 0.87 [0.73, 1.04] 24.72 [7.58, 80.60]
Qureshi 12.6 [3.8, 41.4] 0.87 [0.74, 1.02] 12.87 [4.75, 34.88]
Sevene 0.9 [0.1, 13.5] 1.00 [0.96, 1.05] 0.83 [0.05, 13.53]

ACC (American College of Cardiology), AHA (American Heart Association), BP (blood pressure), dBP (diastolic BP), -LR- (negative likelihood ratio), +LR (positive likelihood ratio), sBP (systolic BP), UTD (unable to determine), CI (Confidence interval), PI (prediction interval)

Slade. The diagnostic accuracy of American College of Cardiology-American Heart Association blood pressure categories for identification of women and babies at risk. Am J Obstet Gynecol 2023.