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. 2023 Apr;228(4):418–429.e34. doi: 10.1016/j.ajog.2022.10.004

Table S9.

Pooled relative risk and mean likelihood ratios for perinatal death, according to BP cut-offs at <20 weeks, determined by ACC/AHA BP categories

COMPARATOR
BP measured at <20 weeks Ref RR [95% CI]
I2, (95% PI)
-LR +LR
Diagnostic threshold: sBP 120mmHg (with dBP <80mmHg)
Pooled Normal (<120/80 mmHg) 1.4 [1.2, 1.6]
I2=11%, (1.1, 1.7)
0.94 [0.90, 0.97] 1.34 [1.17, 1.54]
Bellad 1.4 [1.1, 1.9] 0.98 [0.95, 1.00] 1.44 [1.06, 1.95]
Greenberg 1.7 [1.1, 2.5] 0.84 [0.72, 0.99] 1.40 [1.09, 1.80]
Qureshi 1.4 [1.2, 1.7] 0.93 [0.90, 0.97] 1.40 [1.20, 1.65]
Reddy 0.9 [0.6, 1.4] 1.02 [0.91, 1.14] 0.94 [0.67, 1.31]
Sevene 1.1 [0.5, 2.6] 0.98 [0.88, 1.10] 1.12 [0.52, 2.43]
Diagnostic threshold: sBP 130mmHg or dBP 80mmHg
Pooled Normal + Elevated BP (<130/80 mmHg) 1.6 [1.4, 1.9]
I2=0%, (1.2, 2.1)
0.95 [0.92, 0.97] 1.59 [1.29, 1.94]
Bellad 1.9 {1.4, 2.7] 0.97 [0.96, 0.99] 1.97 [1.36, 2.86]
Greenberg 1.8 [1.1, 2.9] 0.90 [0.80, 1.00] 1.62 [1.12, 2.35]
Qureshi 1.6 [1.3, 1.9] 0.95 [0.92, 0.98] 1.58 [1.28, 1.94]
Reddy 1.1 [0.6, 1.8] 0.99 [0.92, 1.07] 1.05 [0.65, 1.68]
Sevene 1.5 [0.5, 3.9] 0.97 [0.89, 1.06] 1.47 [0.55, 3.90]
Diagnostic threshold: sBP 140mmHg or dBP 90mmHg
Pooled Normal + Elevated BP +Stage 1 HTN (<140/90 mmHg) 2.4 [1.8, 3.1]
I2=0%, (1.5, 3.8)
0.98 [0.95, 0.99] 2.54 [1.76, 3.56]
Bellad 2.1 [1.2, 3.8] 0.99 [0.98, 1.00] 3.60 [1.75, 7.38]
Greenberg 3.2 [1.7, 5.7] 0.93 [0.86, 1.00] 2.00 [1.20, 3.32]
Qureshi 2.3 [1.5, 3.5] 0.98 [0.97, 1.00] 2.59 [1.52, 4.43]
Reddy 1.4 [0.3, 5.7] 0.99 [0.97, 1.02] 1.40 [0.35, 5.58]
Sevene 2.3 [0.6, 8.6] 0.97 [0.92, 1.04] 2.41 [0.56, 10.30]

ACC (American College of Cardiology), AHA (American Heart Association), BP (blood pressure), dBP (diastolic BP), -LR (negative likelihood ratio), +LR (positive likelihood ratio), sBP (systolic BP), CI (confidence interval), PI (prediction interval)

Slade. The diagnostic accuracy of American College of Cardiology-American Heart Association blood pressure categories for identification of women and babies at risk. Am J Obstet Gynecol 2023.