Table 3.
Summary of relevant observational studies and clinical trials of the efficacy/effectiveness of zona vaccination on the prevention of cardiovascular events in older adults
| Author | Year of publication | Journal | Study design | Country | Follow-up | Specific-disease | N | Age (years) | Vaccination (yes) | Outcomes | Protective effect (Y/N) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Klaric et al | 2019 | Military Medicine | Retrospective cohort study | USA | / | / | 265,568 | Subgroup analysis (≥ 65 y) | 63,166 | Strokes | Y |
| Yang et al | 2021 | Stroke | Prospective cohort study | USA | 5.1 y | / | 3,206,812 | ≥ 65 y | 1,603,406 | Stokes | Y |