Table 1.

Percentage activity of KpLpxH in the presence of 0.1 μM LpxH inhibitors

Compounds	Structure	Percentage Activity[a]	Percentage Inhibition
1 (AZ1)		78[16]	22[16]
2 (JH-LPH-33)		21[16]	79[16]
3 (JH-LPH-41)		36[16]	64[16]
7		30 ± 6	70
8		18 ± 1	82
10		93 ± 7	7
12		57 ± 3	43
13		3 ± 2	97
15		39 ± 6	61
18		34 ± 7	66
20		59 ± 7	41

^[a]Percentage activity was normalized against the specific activity of KpLpxH measured in the presence of 10% DMSO (309 ± 12 μmol/min/mg). Errors represent the standard percent error.