Table 5.
Results of Autologous Hematopoietic Stem Cell Transplant in Pediatric Relapsed/Refractory Lymphoblastic Lymphoma
| Author (Reference) | N. Patients | Age (Years) | Years | Disease Status Before HSCT | Outcome (Years) |
|---|---|---|---|---|---|
| Won (2006)70 | 14 auto | < 18 | 1997–2004 | CR, no CR | EFS 50% (2) |
| Mitsui (2009)85 | 33 (auto 7, allo 26) | < 15 | 1996–2004 | CR, PR, PD | OS 43.2% (3) |
| Gross (2010)78 | 53 (auto 14, allo 39) | < 18 | 1990–2005 | NR | EFS 4% auto; 40% allo (5) |
| Burkhardt (2009)86 | 14 (auto 2, allo 12) | < 18 | 1990–2003 | CR, PR | CCR 0 auto; 5/12 allo |
| Michaux (2016)87 | 10 (auto 2, allo 8) | < 18 | 1997–2008 | CR, PR, PD | 2/2 deaths auto; 2/8 alive allo |
| Burkhardt (2021)65 | T-LBL 177 (auto 12, allo 89) B-LBL 34 | < 18 | 2000 - NR | CR, PR | T-LBL: OS 33% auto; 44% allo (8) B-LBL: OS 52% (8) |
Abbreviations: Allo, allogeneic transplant; auto, autologous transplant; EFS, event free survival; CCR, continuous complete remission; CR, complete remission; HSCT, hematopoietic stem cell transplant; LBL, lymphoblastic lymphoma; NR, not reported; OS, overall survival; PD, progressive disease; PR, partial remission.