L1: The first laser treatment; L2: the second laser treatment; L3: the third laser treatment.
T0: A screening visit two to four weeks before the first laser treatment (baseline); T1: follow-up visits one month after L3; T3: follow-up visits three months after L3; T6: follow-up visits six months after L3; T12: follow-up visits 12 months after L3; T24: follow-up visits 24 months after L3.
Each date shows average ± standard deviation. *: Significant difference between the two groups.
VEL: vaginal erbium SMOOTH mode laser treatment; VEL+Nd:YAG: VEL and neodymium-doped yttrium-aluminum-garnet laser combination treatment