Comparison of permeation of NAC for each formulation. Comparative analysis of permeation of NAC depending on each formulation (B1 [in DW], PF1 [in DPG], PF8 [ TPGS in DPG], CF2 [benzalkonium chloride in DPG], NF1 [Tween®80 in DPG]). The permeation study was performed with the Strat-M® membrane through the Franz diffusion cell system at 32 ± 1 °C for 24 h. Data are expressed as mean ± standard deviation (sd, n = 3).