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. 2023 Jun 5:1–29. Online ahead of print. doi: 10.1007/s12671-023-02148-x

Table 1.

Characteristics of the Included Studies

Reference; Country Participants; Mean age; Female (%) Descriptions of intervention and comparison/control groups Relevant outcomes (measures); Data collection time points; Relevant results (between-group differences over time only) Overall RoB
Al-Refae et al. (2021); Canada 165 adults who owned an iPhone (a diagnosis with a mental health disorder—25%); 25.24 years; 78.8%

- IG: A 4-week self-compassion-based smartphone app intervention combined with cognitive restructuring training (Serene) involving psychoeducation about self-compassion, mindfulness meditations, mindful journaling and self-compassionate writing, and cognitive restructuring (i.e., identification and modification of unhelpful thoughts or beliefs and developing and applying actions plans to modify one’s behaviors) (n = 78)

- CG: Waitlist control (n = 87)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest and posttest; IG > CG in DASS-21-D and DASS-21-S over time (p < .05) High
Anuwatgasem et al. (2020); Thailand 44 adults with diagnosis of MDD; NR; NR

- IG: 7 weekly sessions (1.5 hr per session) of group-based self-compassion-based therapy (n = 23)

- CG: Standard psychotherapy group (n = 11)

Depressive symptoms (MADRS), anxiety (HADS-A), and stress (PSS); Pretest and posttest; No significant between-group differences in outcomes over time High
Arimitsu (2016); Japan 40 individuals with low self-compassion (SCS < 17.35, which is the average score in a Japanese sample); 21.34 years; 75%

- IG: 7 weekly sessions (1.5 hr per session) of a group-based self-compassion program involving loving-kindness meditation practice, mindfulness training, compassionate imagery skill training, compassionate letter writing, and practice of compassionate behaviors (n = 20)

- CG: Waitlist control (n = 20)

Depressive symptoms (BDI-II) and anxiety (STAI); Pretest, posttest, and 3-month F/U; CG > IG in STAI over time (p = .05) High
Beaumont et al. (2012); UK 32 people with a traumatic incident (e.g., car accidents and accidents at work); NR; NR

- IG: 12 sessions of self-compassion training and CBT involving compassionate letter writing and use of imagery by bringing to mind a loving, accepting, and caring image (n = 16)

- CG: 12 sessions of CBT covering cognitive restructuring, behavioral activation, graded exposure, relapse prevention, and Socratic dialog (n = 16)

Depressive symptoms (HADS-D) and anxiety (HADS-A); Pretest and posttest; IG > CG in HADS-D over time (p < .001) High
Beshai et al. (2020); USA 456 adults with mild to moderate levels of depression, anxiety, or stress; 35.13 years; 43.9%

- IG: 4 weekly modules of a self-guided online self-compassion intervention involving psychoeducational videos introducing concepts, audio-guided mindfulness and loving-kindness meditation practice, and self-kindness practice (e.g., Self-Compassion Break exercise) (n = 227)

- CG: Watching nature videos superimposed onto relaxing meditation music for 4 weeks (watching one video per week) (n = 229)

Depressive symptoms (PHQ-9), anxiety (GAD-7), and stress (PSS); Pretest and posttest; IG > CG in GAD-7 (p < .05) and PSS over time (p = .001) Unclear
Bluth et al. (2016); USA 34 adolescents (aged 14 to17 years) with depressive symptoms—score < 13 on a modified KADS; NR; 74%

- IG: 6 weekly sessions (1.5 hr per session) of a mindful self-compassion adolescent program involving psychoeducation regarding self-compassion, hands-on activities and practices for self-compassion, and guided audio and video recordings of self-compassion practices for home practice (n = 16)

- CG: Waitlist control (n = 18)

Depressive symptoms (SMFQ), anxiety (STAI), and stress (PSS); Pretest and posttest; IG > CG in SMFQ over time (p < .01) Unclear
Boggiss et al. (2020); New Zealand 27 adolescents (aged 12 to 16 years) with type 1 diabetes and a moderate to high instance of disordered eating behaviors as assessed by the DEPS-R; 13.9 years; 60%

- IG: Two sessions (2.5 hr per session) of a self-compassion intervention delivered 1 week apart involving group exercises and discussions, art activities, meditations, and individual reflection exercises exploring the three components of self-compassion and self-compassion coping tools to use in everyday life when experiencing difficult emotions (n = 13)

- CG: Waitlist control (n = 14)

Stress (PSS); Pretest and posttest; No significant between-group difference in PSS over time High
Cândea and Szentágotai-Tătar (2018); Romania 136 undergraduate students with social anxiety disorder (30 ≤ LSAS-SR); 21.85 years; 88.23%

- IG: A 2-week self-compassion online training that involved explanation of self-compassion and exercises (n = 42)

- CG1: A 2-week cognitive reappraisal online training that involved explanation of reappraisal and exercises (n = 51)

- CG2: Waitlist control (n = 43)

Anxiety (LSAS-SR); Pretest and posttest; No significant between-group difference in LSAS-SR over time High
Carlyle et al. (2019); UK 38 adults (aged 22 to 62 years) who had a diagnosis of opioid use disorder and took a daily opioid substitute medication; 39.95 years; 36.84%

- IG: 3 weekly sessions (2 hr per session) of a self-compassion training program that involved psychoeducation regarding self-compassion and self-compassion exercises (e.g., compassionate body scan and writing a compassionate letter to self and an ideal compassionate self) with guided audio recordings for home practice (n = 15)

- CG1: 3 weekly sessions (2 hr per session) of a relaxation training program that involved psychoeducation regarding relaxation and relaxation exercises (e.g., belly breathing and progressive muscle relaxation) with guided audio recordings for home practice (n = 12)

- CG2: Waitlist control (n = 11)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest and posttest; No between-group differences in outcomes over time Unclear
Collado‐Navarro et al. (2021); Spain 90 adult outpatients (aged 18 to 75 years) with mild to moderate depressive and/or anxious disorder; 46.34 years; 86.67%

- IG: 8 weekly sessions (2 hr per session) of a group-based self-compassion program that involved psychoeducation, 30-min daily simple exercises with audio files, meditation, visualizations, and practices for self-compassion (n = 30)

- CG1: 8 weekly sessions (2 hr per session) of a group-based MBSR program that involved meditation, individual and group dialogs and inquiries about perceptions and habits, and home practice (n = 30)

- CG2: TAU (n = 30)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest, posttest, and 6-month F/U; IG & CG1 > CG2 in DASS-21 subscales over time (p < .05) Unclear
D'Alton et al. (2019); Ireland 94 adults (≥ 18 years) with mild to moderate psoriasis; 49.89 years; 55.3%

- IG: 8 weekly sessions (2 hr per session) of a group-based mindfulness-based self-compassion program that involved guided self-compassion meditations (e.g., compassionate body scan), exercises (e.g., eyes on exercise), psychoeducation, and group discussion about the meditations and exercises with guided audio meditation recordings for daily mindfulness practice (n = 25)

- CG1: 8 weekly sessions (2 hr per session) of a group-based MBCT program that involved guided mindfulness meditations, sharing experiences of these exercises, and teaching cognitive behavioral skills and techniques (e.g., cognitive defusion and recording pleasant events) with guided audio meditation recordings for daily mindfulness practice (n = 25)

- CG2: TAU (n = 22)

Depressive symptoms (HADS-D) and anxiety (HADS-A); Pretest, posttest, 6-month F/U, and 12-month F/U; No significant between group differences in outcomes over time High
DeTore et al. (2022); USA 107 undergraduate students with mild to moderate depressive symptoms; 18.82 years; 71.03%

- IG: 4 weekly group sessions (1.5 hr per session) addressing self-compassion skill practice (e.g., self-compassion break, mindfulness exercise, self-compassion writing exercise, and self-compassion letter writing) with home practice (e.g., 3-min breathing exercise and self-compassion mindfulness exercise) (n = 54)

- CG: Waitlist control (n = 53)

Depressive symptoms (BDI) and anxiety (STAI); Pretest, posttest, and 12-month F/U; IG > CG in BDI (p < .001) and STAI over time (p < .05) Unclear
Dundas et al. (2017); Norway 158 university students; 25 years; 85%

- IG: 3 sessions (1.5 hr per session) of a self‐compassion course delivered over 2 weeks that involved lectures, self-compassion exercises, group discussions, and experiential practices with audio guides to self-compassion exercises for daily use (n = 69)

- CG: Waitlist control (n = 69)

Depressive symptoms (MDI) and anxiety (STAI); Pretest and posttest; IG > CG in MDI (p < .05) and STAI over time (p < .001) High
Eriksson et al. (2018); Sweden 101 practicing psychologists; 36.2 years; 96.04%

- IG: A 6-week web-based mindful self-compassion program involving 15-min exercises per day, 6 days per week, for 6 weeks for self-compassion exercises with guided instructions as audio files such as loving kindness, pause for self-compassion, and body scan (10 hr in total) (n = 52)

- CG: Waitlist control (n = 49)

Stress (PSS); Pretest and posttest; IG > CG in PSS over time (p < .001) High
Fernandes et al. (2022); Portugal

292 postpartum mothers (≥ 18 years) of a child (aged up

to 18 months) with moderate or high levels of

parenting stress; 34.03 years; 100%

- IG: 6 weekly modules (1 hr per module) of a self-guided, web-based, mindful, and compassionate parenting training with written materials, visual elements, audio tracks, and homework tasks, addressing psychoeducational materials, formal mediation practices (e.g., breath meditation), self-compassion practices, and mindful parenting exercises (n = 146)

- CG: Waitlist control (n = 146)

Depressive symptoms (EPDS), anxiety (HADS-A), and stress (Parental Stress Scale); Pretest and posttest; IG > CG in parental stress over time (p = .05) High
Friis et al. (2016); New Zealand 63 adult patients (aged 18 to 70 years) with type 1 or type 2 diabetes; 44.37 years; 68.25%

- IG: 8 weekly sessions (2.5 hr per session) of a group-based mindful self-compassion program that involved general introduction of self-compassion, developing a compassionate inner voice, and skills practice for self-compassion and mindfulness (n = 32)

- CG: Waitlist control (n = 31)

Depressive symptoms (PHQ-9) and stress (DDS); Pretest, posttest, and 3-month F/U; IG > CG in PHQ-9 (p < .05) and DDS over time (p < .001) Unclear
Gammer et al. (2020); UK 206 mothers (≥ 18 years) of infants younger than 1 year; 35.19 years; 100%

- IG: 5 weekly sessions of a web-based self-compassion program over 5 to 6 weeks that involved 10–15 min per week for contents and a few minutes per day for exercises with a written description and an audio guide (n = 105)

- CG: Waitlist control (n = 101)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest, posttest, and 6-week F/U; No significant between group differences in outcomes over time Unclear
Guo et al. (2020); China 314 female adults (aged 18 to 40 years) who were in the second or third trimester of pregnancy before 34 weeks and had antenatal depressive or anxiety symptoms (EPDS ≥ 9); 30.6 years; 100%

- IG: A 6-week web-based mindful self-compassion program that involved 10 hr of training with 36 mini-sessions in total (15 min per session, 6 mini-sessions a week) and used self-compassion exercises with guided instructions (n = 157)

- CG: Waitlist control (n = 157)

Stress (PSI); baseline, 3 months, and 1 year postpartum; IG > CG in PSI over time (p < .05) High
Hasselberg and Rönnlund (2020); Sweden 56 young adults (aged 18 to 25 years); 22.3 years; 89.29%

- IG: A 2-week web-based self-help self-compassion program (15 min of training per day, 5 days a week) that involved a prerecorded psycho-educative introduction of self-compassion and guided exercises of prerecorded video clips such as loving kindness meditation, breathing exercises, and body scan (n = 28)

- CG: Waitlist control (n = 28)

Stress (PSS); Pretest and posttest; IG > CG in PSS over time (p < .01) High
Haukaas et al. (2018); Norway 81 undergraduate and graduate students (63%—mild to severe depression; 64.2%—mild to severe anxiety); 22.9 years; 75.3%

- IG: 3 weekly sessions (45 min per session) of a group-based mindful self-compassion program that involved guided meditation and exercises designed to promote self-compassion (e.g., affectionate breathing and loving kindness meditation) provided with prerecorded audiotapes for daily practice (n = 41)

- CG: 3 weekly sessions (45 min per session) of a group-based attention training program that involved a 12-min auditory exercise designed to strengthen attentional control and promote external focus of attention provided with prerecorded audiotapes for daily practice (n = 40)

Depressive symptoms (PHQ-9) and anxiety (GAD-7); Pretest, posttest, and 6-month F/U; No significant between group differences in outcomes over time Unclear
Held and Owens (2015); USA 27 homeless male veterans who were living in transitional housing facilities; 51.3 years; 0%

- IG: A 4‐week self‐administered self‐compassion training that involved a workbook (e.g., learning to respond compassionately to one’s own experiences and compassionate letter writing) and 5- to 15-min daily exercises (n = 13)

- CG: A 4-week self-administered stress management training that involved a workbook (e.g., deep breathing and progressive muscle relaxation) and 5- to 15-min daily exercises (n = 14)

Stress (PCL-S); Pretest and posttest; CG > IG in PCL-S over time (p < .01) Unclear
Huang et al. (2021); China 69 college students; 20.55 years; 71.21%

- IG: 4 weekly sessions (2 hr per session) of a group-based self-compassion program that involved psychoeducation about self-compassion and self-compassion skills training (e.g., affectionate breathing meditation and loving-kindness meditation) (n = 32)

- CG: Waitlist control (n = 37)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest, posttest, and 1-month F/U; IG > CG in DASS-21-D (p < .001) and DASS-21-S over time (p < .05) High
Javidi et al. (2023); Australia 82 adults (aged 18 to 65 years) with a primary diagnosis of either a depressive disorder or PTSD; 38.75 years; 74.2%

- IG: 12 sessions of an individual self-compassion training program combined with behavioral therapy (i.e., behavioral activation within CBT) that involved psychoeducation on three elements of self-compassion, practice taking a self-compassion break, compassionate letter writing to self, and building a self-compassionate image (n = 41)

- CG: 12 sessions of an individual CBT program that involved psychoeducation, cognitive restructuring, and behavioral activation (n = 41)

Depressive symptoms (PHQ-9) and stress (K10); Pretest and posttest; IG > CG in PHQ-9 (p < .01) and K10 over time (p < .001) High
Kelly and Carter (2015); Canada 41 adults (> 18 years) with binge eating disorder; 45 years; 82.93%

- IG: 3 weeks of self-help self‐compassion exercises that involved an audio-guided PowerPoint slideshow for psychoeducation on development of a structured eating plan and self-compassion, practice of guided exercises (e.g., two self-compassion imagery exercises and compassionate letter writing to self), and instructions to cultivate a self-compassionate mindset through imagery, self-talk, and letter-writing over 3 weeks plus provision of a link to an online form for self-compassion practice (e.g., self-compassionate imagery visualization and compassionate letter writing to self) every evening before bed (n = 15)

- CG1: 3 weeks of self-help behavioral strategies that involved an audio-guided PowerPoint slideshow for psychoeducation on development of a structured eating plan and behavioral activation, such as developing alternate activities with which to replace binge eating when urges arise and monitoring and reviewing strategies used when urges to binge arose over the 3 weeks (n = 13)

- CG2: Waitlist control (n = 13)

Depressive symptoms (CES-D); Pretest and posttest; No significant between group difference in CES-D over time Unclear
Kelly et al. (2009); Canada 75 adults (≥ 18 years) who suffered from chronic facial acne and experienced significant acne-related distress (≥ 4 on the SKINDEX-16’s emotion distress subscale); 22 years; 77.33%

- IG: A 2-week online self-help self-soothing intervention that involved a 1-hr PowerPoint session for the rationale, instructions, and exercises for self-compassionate imagery and self-talk (e.g., visualizing a self-compassionate image, writing a self-compassionate letter, and developing self-compassionate phrases) with daily self-help exercises for 2 weeks (e.g., repeating their compassionate self-statements three times per day while engaging in compassionate imagery) (n = 23)

- CG1: A 2-week online attack-resisting intervention that involved a 1-hr PowerPoint session for the rationale, instructions, and exercises for resilient and retaliating imagery and self-talk exercise with daily self-help exercises for 2 weeks (n = 26)

- CG2: TAU (n = 24)

Depressive symptoms (BDI) and stress (SKINDEX-16); Pretest and posttest; CG1 > CG2 in BDI (p < .01), IG and CG1 > CG2 in SKINDEX-16 over time (p < .01) Unclear
Kelman et al. (2018); USA & India 84 women (≥ 18 years) who were pregnant, became pregnant within the last year, and intend to become pregnant in the future (aged 18 to 54 years); NR; 100%

- IG: A 2-week internet-based compassionate mind training that involved a 45‐min didactic course that introduced the course materials and audio meditations delivered by email three times over the 2-week period (e.g., finding ourselves here in the flow of life and cultivating the compassionate self) (n = 41)

- CG: A 2-week internet-based CBT that involved a 45‐min didactic course that introduced the course materials (i.e., thoughts, activities, assertiveness, and sleep) and exercises for CBT delivered by email three times over the 2-week period (n = 43)

Depressive symptoms (Depression subscale of the PHQ-4) and anxiety (Anxiety subscale of the PHQ-4); Pretest and posttest; IG > CG in outcomes over time (p < .05) High
Krieger et al. (2019); Switzerland 122 adults (≥ 18 years) with increased levels of self-criticism (≥ 20 on the inadequate self subscale of the FSCRS; 37.69 years; 77.69%

- IG: 7 weekly modules (1 hr per module) of internet-delivered self-help self-compassion training (texts, audio files, and a diary function) that covered descriptions of self-compassion (e.g., common humanity, self-criticism vs. self-kindness, and over-identification vs. mindfulness) and exercises (e.g., mindfulness exercises, loving-kindness meditation, and self-compassionate writing) (n = 60)

- CG: TAU (n = 62)

Stress (DASS-21); Pretest and posttest; IG > CG in DASS-21 over time (p < .01) Unclear
Lennard et al. (2021); Australia 248 mothers (≥ 18 years) of infants (< 2 years); 32.56 years; 100%

- IG: An 8-week online self-compassion intervention that involved two videos covering psychoeducation about self-compassion in the context of motherhood and a guided self‐compassion visualization exercise with a downloadable tip sheet offering ideas for becoming more self‐compassionate and SMS reminders (n = 94)

- CG: Waitlist control (n = 154)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest and posttest; No significant between-group differences in outcomes over time High
Mak et al. (2018); Hong Kong 2161 adults (> 18 years) who owned a mobile device and had consistent internet access; 33.64 years; 72.88%

- IG: 4 weekly modules (28 daily sessions, 10–15 min daily) of a mobile app–based self-compassion program that involved reading and graphic contents and audio-guided self-compassion exercises (e.g., compassionate body scan, affectionate breathing, loving-kindness meditation, compassionate walking, soften-allow-soothe, self-compassion break, and self-compassion journaling) (n = 705)

- CG1: 4 weekly modules (28 daily sessions, 10–15 min daily) of a mobile app–based cognitive behavioral psychoeducation program that involved problem-solving skills, emotional management skills, cognitive strategies to tackle automatic negative thoughts associated with stress, audio-guided relaxation skills training (e.g., progressive muscle relaxation and imagery relaxation), and information and graphics about mental health, stress, and cognitive behavioral approach for mental health (n = 753)

- CG2: 4 weekly modules (28 daily sessions, 10–15 min daily) of a mobile app–based mindfulness program that involved audio-guided mindfulness exercises (e.g., body scan, mindful breathing, mindful eating, mindful walking, and thought-distancing exercise) and readings and graphics to explain concepts of mindfulness (n = 703)

Stress (K6); pretest, posttest, and 3-month F/U; No significant between group difference in K6 over time High
Martínez-Borrás et al. (2022); Spain 40 employees of an automotive company; 41.93 years; 37.5%

- IG: 6 weekly in-person sessions (12 hr in total) of a group-based workplace mindfulness- and self-compassion-based intervention, involving meditation practices and psychoeducation to foster mindfulness and self-compassion to cope with

work-related stress (n = 20)

- CG: A 6-week, 3-session, in-person group-based workplace stress management program involving psychoeducation regarding work-related stress and coping strategies (n = 20)

Stress (PSQ); Pretest and posttest; IG > CG in PSQ over time (p < .05) High
Matos et al. (2017); Portugal 93 adults, including college students (78.5%); 23.34 years; 90.3%

- IG: A 2-week self-compassion program involving a 2-hr group session introducing concepts of self-compassion and compassionate mind training practices and audio files for 2-week independent practice (e.g., an imagery practice to develop a compassionate image of another mind that has caring intent toward the self) (n = 56)

- CG: Waitlist control (n = 37)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest and posttest; IG > CG in DASS-21-S over time (p < .05) High
Matos et al. (2022); Portugal 155 public school teachers; 51.35 years; 92.9%

- IG: 8 weekly sessions (2.5 hr per session) of a group-based compassionate mind training program for teachers aiming to cultivate a compassionate self by using psychoeducation and self-compassion practices (e.g., cultivating the ideal compassionate self, self-compassion break, and mindful breathing) (n = 80)

- CG: Waitlist control (n = 75)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest, posttest, and 3-month F/U; No significant between group differences in outcomes over time High
Mifsud et al. (2021); Australia 79 breast cancer survivors (≥ 18 years) who reported at least one negative event related to the changes that occurred to their body after breast cancer; 58.6 years; 100%

- IG: A 3-week web-based self-compassion training that included a 30-min self-compassion focused writing activity (e.g., writing a self-compassionate letter to self) to address three components of self-compassion and listening to a 5-min self-compassion based audio meditation each day for 3 weeks with a daily SMS reminder (n = 17)

- CG1: A web-based 30-min expressive writing activity about a challenging body image experience, including event details, thoughts, and feelings (n = 23)

- CG2: A web-based 30-min self-compassion focused writing activity, including writing a self-compassionate letter to self, to address three components of self-compassion (n = 39)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest and posttest; No significant between group differences in outcomes over time Low
Nadeau et al. (2021); USA 57 women; 38.12 years; 100%

- IG: A 10-week online self‐guided self-compassion course that involved video-recorded psychoeducational lectures, an interview with a prominent expert in the field, guided experiential exercises, case interviews, and homework (n = 25)

- CG: Waitlist control (n = 32)

Depressive symptoms (CES-D) and anxiety (GAD-7); Pretest, posttest, and 1-month F/U; No significant between group differences in outcomes over time High
Navab et al. (2019); Iran 20 mothers (aged 20 to 40 years) of children with ADHD; 30.65 years; 100%

- IG: 8 weekly sessions (1.5 hr per session) of a self-compassion-based program that included understanding the differences between self-compassion and self-pity, mindfulness training, developing warmth and kindness toward oneself, practicing affectionate self-image, and writing a self-compassionate letter (n = 10)

- CG: Waitlist control (n = 10)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest and posttest; IG > CG in DASS-21-D and DASS-21-A over time (p ≤ .01) High
Neff and Germer (2013); USA 51 adults (77% with a graduate degree; 76% with prior meditation experience); 50.16 years; 80%

- IG: 8 weekly sessions (2 hr per session) of a group-based mindful self-compassion program that involved an introduction to self-compassion and mindfulness, application of self-compassion in daily life, development of a compassionate inner voice, the importance of value-focused living, skills training for difficult emotions and challenging relationships, and how to relate to positive aspects of oneself and one’s life with appreciation, with a half-day retreat for mindfulness training between session 4 and 5 (n = 24)

- CG: Waitlist control (n = 27)

Depressive symptoms (BDI), anxiety (STAI), and stress (PSS); Pretest and posttest; IG > CG in BDI and STAI (p < .01) and in PSS over time (p < .05) High
Noorbala et al. (2013); Iran 19 female adults (aged between 20 and 40 years) with diagnosis of MDD and BDI ≥ 20; 28.15 years; 100%

- IG: 12 sessions (2 hr per session, two sessions per week) of a group-based mindful self-compassion training delivered for 6 weeks that involved introducing concepts of self-compassion, exploring the way they thought about themselves and how they behave toward themselves, and exercises (e.g., compassionate imagery, soothing breathing rhythm, mindfulness, and compassionate letter writing) (n = 9)

- CG: TAU (n = 10)

Depressive symptoms (BDI-II) and anxiety (AS); pretest, posttest, and 2-month F/U; IG > CG in outcomes over time (p < .05) High
Preuss et al. (2021); Germany 217 parents (≥ 18 years) of at least one child aged 3 to 18 years who had mild depression and stress based on DASS-21 at baseline; 40.63 years; 92.6%

- IG: Two online video sessions (a 20-min video session on Day 1 and a 10-min video session on Day 3) of a self-compassion program that involved psychoeducation about possible psychological consequences of pandemic restrictions and the practice of mindfulness (i.e., by naming their burdening emotions and acknowledging their suffering and distress), common humanity (i.e., by internalizing this stressful family moment as a shared human experience of suffering during the pandemic), and self-kindness (i.e., by expressing a kind, warm, and soothing self-talk while strengthening their self-esteem in the parental role), with three email reminders to transfer the application of strategies to daily family life (Days 2, 4, 5) (n = 75)

- CG1: Two online video sessions (same length and format as the IG) of a cognitive reappraisal program that involved psychoeducation and practice of cognitive restructuring techniques, with three email reminders to transfer the application of strategies to daily family life (Days 2, 4, 5) (n = 73)

- CG2: Waitlist control (n = 69)

Stress (PSS); Pretest and posttest (1 week); IG and CG1 > CG2 in PSS over time (p < .001) High
Sajjadi et al. (2022); Iran 47 young adults (aged between 18 to 25 years) with a history of childhood maltreatment; NR; 57%

- IG: 8 weekly sessions (2 hr per session) of a group-based mindful self-compassion program covering the definition of self-compassion and mindfulness with practices (e.g., soothing

touch, affectionate breathing, and compassionate letter to myself) (n = 24)

- CG: TAU (n = 23)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest, posttest, and 2-month F/U; IG > CG in outcomes over time (p < .01) Unclear
Savari et al. (2021); Iran 30 female students (aged between 20 and 30 years) with a diagnosis of major depression confirmed by the SCID-I for DSM-V and by scores at least in the moderate range on the BDI-II total score (> 20); 24.3 years; 100%

- IG: 8 sessions (1.5 hr per session, twice a week) of a group-based self-compassion program that involved psychoeducation about self-compassion, practice of self-compassion exercises (e.g., compassionate self-imagery and compassionate letter writing), and homework assignments (n = 15)

- CG: Waitlist control (n = 15)

Depressive symptoms (BDI-II); Pretest and posttest; IG > CG in BDI-II over time (p < .01) Unclear
Schnepper et al. (2020); Austria and Germany 57 people who wanted to lose weight or develop a healthier eating behavior; 29 years; 84.21%

- IG: A 14-day self-compassion mobile app intervention that involved daily notifications for daily self-compassion exercises (e.g., compassionate breathing exercises, soothing touch, writing a self-compassionate letter, and journaling exercises) (n = 28)

- CG: Waitlist control (n = 29)

Stress (PSS); Pretest and posttest; IG > CG in PSS over time (p < .05) High
Schuling et al. (2020); the Netherlands 122 adults (≥ 18 years) who had been diagnosed with recurrent depressive disorder and had previously participated in an MBCT course (≥ 4 sessions, at least 1 year prior to this study); 55.6 years; 74.6%

- IG: 8 sessions (2.5 hr per session, once every 2 weeks) of a group-based MBCL program that involved self-compassion exercises (e.g., compassionate breathing space, compassionate body scan, and soften-soothe-allow: compassion for self), group inquiry, didactic and interactive teaching, and CDs provided for 30-min daily home practice (n = 61)

- CG: TAU (n = 61)

Depressive symptoms (BDI-II); Pretest and posttest (at 4 months after pretest); IG > CG in BDI-II over time (p < .05) High
Seekis et al. (2020); Australia 76 undergraduate women with high levels of body concerns (≥ 12 on the DT and ≥ 19 on the Body Dissatisfaction Subscale from the EDI-3); 18.04 years; 100%

- IG: A 50-min in-person group-based mindful self-compassion workshop (i.e., psychoeducation on self-compassion, two brief writing exercise for a self-compassionate mindset, and practice of compassionate body scan) and a 2-week online group discussion (i.e., use of self-compassion techniques when experiencing appearance distress and posting about their experiences on a private Facebook group three times per week for 2 weeks) (n = 42)

- CG: Waitlist control (n = 34)

Anxiety (SAAS); Pretest, posttest, 1-month F/U, and 3-month F/U; No significant between group difference in SAAS over time Unclear
Shahar et al. (2015); Israel 38 adults (aged 18 to 65 years) with high levels of self-criticism (≥ 30 on the SCP subscale of the DAS); 30.62 years; 60.53%

- IG: 7 weekly sessions (1.5 hr per session) of a group-based loving‐kindness meditation program involving self-compassion practices and group discussions and provision of CDs of guided meditations for daily home practice (n = 19)

- CG: Waitlist control (n = 19)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest, posttest, and 3-month F/U; IG > CG in DASS-21-D over time (p < .05) Unclear
Shapira and Mongrain (2010); Canada 1002 adults (aged 18 to 72 years) who had moderate levels of depressive symptoms as measured by the CES-D; 34 years, 81.54%

- IG: 1-week online daily exercises for self-compassion that involved thinking about a distressing event that occurred that day and writing a self-compassionate letter (n = 63)

- CG1: 1-week online daily exercises for optimistic thinking that involved visualizing and writing a letter about a future in which current issues were resolved and giving themselves advice on how to get there (n = 55)

- CG2: writing freely about an early memory daily online for 1 week (n = 70)

Depressive symptoms (CES-D); Pretest, posttest, 1-month F/U, 3-month F/U, and 6-month F/U; IG and CG1 > CG2 in CES-D over time (p < .05) High
Sommers-Spijkerman et al. (2018); the Netherlands 242 adults (≥ 18 years) with low to moderate levels of well-being, as determined by the MHC-SF; 52.87 years; 74.8

- IG: 7 weekly modules of a guided self-help compassion program with self-compassion as the primary focus over a 9-week period that involved psychoeducational information on an important aspect of self-compassion and experiential exercises with audio guided recordings (e.g., mindful breathing, keeping a diary of self-critical thoughts, and visualizing one’s ideal compassionate self) with weekly email guidance (n = 120)

- CG: Waitlist control (n = 122)

Depressive symptoms (HADS-D), anxiety (HADS-A), and stress (PSS); Pretest, posttest, and 3-month F/U; IG > CG in outcomes over time (p < .001) Unclear
Stevenson et al. (2019); Australia 119 adults (≥ 18 years) with elevated levels of social anxiety (≥ 19 on the SPIN); 29.04 years; 76.5%

- IG: A 14-day online daily self-compassion exercise program that included writing a self-compassionate letter (n = 60)

- CG: A 14-day online daily cognitive restructuring program that included identifying a recent social situation causing social anxiety, negative automatic thoughts experienced during or after the situation evidence, and an alternative evaluation of the situation (n = 59)

Depressive symptoms (DASS-21-D) and anxiety (SPS); Pretest, posttest, 1-week F/U, and 5-week F/U; No significant between group differences in outcomes over time Unclear
Teale Sapach et al. (2023); Canada 59 adults (≥ 18 years) with a primary diagnosis of social anxiety disorder; 34.3 years; 67.8%

- IG: 6 weekly sessions of a web-based, audio-guided self-compassion training program that covered psychoeducation about self-compassion and self-compassion practice exercises (n = 20)

- CG1: 6 weekly sessions of a text-based self-guided applied relaxation training that covered progressive muscle relaxation, cue-controlled relaxation, rapid relaxation, and applied relaxation in anxiety-provoking situations (n = 19)

- CG2: Waitlist control (n = 20)

Anxiety (LSAS-SR); Pretest, posttest, and 3 month F/U; IG > CG2 in LSAS-SR over time (p < .05) & IG = CG1 High
Torrijos‐Zarcero et al. (2021); Spain 123 adults (≥ 18 years) with chronic pain who had a score ≥ 8 on the HADS-A and/or HADS-D and was diagnosed with adjustment disorder, dysthymia or MDD according to the DSM-V; 48.76 years; 87.8%

- IG: 8 weekly sessions (2.5 hr per session) of a group-based mindful self‐compassion program that involved psychoeducation on self-compassion and self-compassion practices (e.g., affectionate breathing, loving-kindness meditation, self-compassionate letter writing, and self-appreciation exercise) (n = 62)

- CG: 8 weekly sessions (2.5 hr per session) of group-based CBT that involved psychoeducation about chronic pain and the relationship among thoughts, emotions, and physical reactions; relaxation and breathing techniques; cognitive restructuring; behavioral activation; and paced physical activity to prevent pain (n = 61)

Depressive symptoms (HADS-D) and anxiety (HADS-A); Pretest and posttest; IG > CG in HADS-A over time (p < .05) High
Urken and LeCroy (2021); USA 203 English-speaking adults (≥ 18 years) with a diagnosis of mental disorders (i.e., MDD, bipolar disorder, schizophrenia, or schizoaffective disorder)—85% MDD; 34.59 years; 72.9%

- IG: A 3-day online self-compassion writing intervention that involved writing with self-compassion prompts focused on three components of self-compassion (i.e., mindfulness, common humanity, and self-kindness) daily for 15 min for 3 days (e.g., writing a self-compassionate letter) (n = 101)

- CG: Writing about how they spent their time leaving out emotions with writing prompts daily for 3 days online (n = 102)

Depressive symptoms (RDQ); Pretest, posttest (after the 3-day intervention), and 1-month F/U; No significant between group difference in RDQ over time High
Weibel et al. (2017); USA 71 undergraduate students; 19.1 years; 77%

- IG: 4 weekly sessions (1.5 hr per session) of a group-based loving-kindness meditation program that included psychoeducation, loving-kindness meditation practice, and group discussion (n = 38)

- CG: Waitlist control (n = 33)

Anxiety (STAI); Pretest, posttest, and 8-week F/U; No significant between group difference in STAI over time High
Williamson (2020); USA 129 students; 19.43 years; 69.77%

- IG: One in-person self-compassion training session (i.e., psychoeducation about self-compassion and interactive exercises involving scenarios) and 10-min daily practice of self-compassion for 3 weeks (e.g., engaging in positive, soothing, self-compassionate self-talk in stressful situations, mindfulness practice, and practicing self-kindness by saying words of comfort to themselves) (n = 44)

- CG1: Time management that involved one in-person meeting and time management practice for 3 weeks (i.e., creating to-do lists of tasks and writing down completed tasks in their activity log and a brief description of how they felt about completing the task) (n = 47)

- CG2: TAU (n = 38)

Depressive symptoms (ZSDS) and stress (PSS); Pretest and posttest; No significant between group differences in outcomes over time High
Wong and Mak (2016); Hong Kong 65 university students; 20.5 years; 53.85%

- IG: Web-based self-compassion writing on 3 consecutive days that involved writing about a recent painful/negative event or any time that they had judged themselves, and then using an accepting and self-compassionate attitude to process the experience provided with three self-compassion prompts (n = 33)

- CG: Web-based control writing according to the instruction on 3 consecutive days that involved writing about daily activities in a factual and unemotional manner (n = 32)

Depressive symptoms (CES-D); Pretest, posttest (1 month F/U), and 3-month F/U; No significant between group difference in CES-D over time High
Woodfin et al., 2021); Norway 89 university students; 27 years; 78.4%

- IG: A 3-week group-based self-compassion program that involved 4 weekly seminars (3 hr per seminar) and a silent retreat (4 hr) and that covered short lectures regarding self-compassion, short guided self-compassion and mindfulness exercises (e.g., affectionate breathing, self-compassion break, and loving-kindness for ourselves), and group discussions (n = NR)

- CG: Waitlist control (n = NR)

Depressive symptoms (MDI) and anxiety (STAI); Pretest and posttest; IG > CG in outcomes over time (p < .01) High
Yadavaia et al. (2014); USA 73 undergraduate students (≥ 18 years) who had low self-compassion (a score on the SCS below the mean score for undergraduates) and high psychological distress (≥ 10 on the GHQ); 20.37 years; 74%

- IG: A 6-hr ACT-based workshop targeting self-compassion that focused on weakening fusion with self-criticism and self-conceptualizations, building self-perspective-taking and self-as-context, and strengthening a value of self-kindness through self-acceptance with experiential exercises for self-compassion (n = 30)

- CG: Waitlist control (n = 43)

Depressive symptoms (DASS-21-D), anxiety (DASS-21-A), and stress (DASS-21-S); Pretest, posttest (at 1 or 2 weeks), and 2-month F/U; IG > CG in DASS-21-D and DASS-21-A over time (p < .05) Unclear
Zheng et al. (2022); China 40 adult (≥ 18 years) with nonspecific chronic low back pain; 35.2 years; 75.7%

- IG: A 4-week self-compassion training, which involved 4 in-person group sessions (2 hr per session) with home practice for psychoeducation about self-compassion and guided self-compassion practices (e.g., affectionate breathing meditation, self-compassion touch, self-compassion writing, and loving kindness meditation for ourselves), combined with core stability exercise (the same exercise condition of CG) (n = 20)

- CG: A 4-week core stability exercise program that involved 4 weekly in-person sessions (1.5 hr per session), self-help exercise at home (30–40 min per session, at least 3 times per week), and completion of an electronic daily training diary (n = 20)

Depressive symptoms (PHQ-9) and anxiety (GAD-7); Pretest, posttest, and 3-month F/U; IG > CG in GAD-7 over time (p < .05) Low

Abbreviations: ADHD, attention-deficit/hyperactivity disorder; AS, Anxiety Scale; BDI, Beck Depression Inventory; CBT, cognitive behavioral therapy; CES-D, Center for Epidemiologic Studies Depression Scale; CG, comparison or control group; DAS, Dysfunctional Attitude Scale; DASS-21-A, Anxiety Subscale of the Depression, Anxiety and Stress Scale—21 Items; DASS-21-D, Depression Subscale of the Depression, Anxiety and Stress Scale—21 Items; DASS-21-S, Stress Subscale of the Depression, Anxiety and Stress Scale—21 Items; DDS, Diabetes Distress Scale; DEPS-R, Diabetes Eating Problem Survey Revised; DSM-V, Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition; DT, Drive for Thinness Scale; EDI-3, Eating Disorder Inventory-3; EPDS, Edinburgh Postnatal Depression Scale; FSCRS, Forms of Self- Criticizing/Attacking and Self-Reassuring Scale; F/U, follow-up; GAD-7, Generalized Anxiety Disorder – 7; GHQ, General Health Questionnaire; HADS-A, Anxiety Subscale of the Hospital Anxiety and Depression Scale; HADS-D, Depression Subscale of the Hospital Anxiety and Depression Scale; IG, intervention group; KADS, Kutcher Adolescent Depression Scale; K6, 6-item Kessler Psychological Distress Scale; K10, 10-item Kessler Psychological Distress Scale; LSAS-SR, Liebowitz Social Anxiety Scale—Self-Report Version; MADRS, Montgomery-Åsberg Depression Rating Scale; MBCL, mindfulness-based compassionate living; MBCT, mindfulness-based cognitive therapy; MBSR, mindfulness‐based stress reduction; MDD, major depressive disorder; MDI, Major Depression Inventory; MHC-SF, Mental Health Continuum-Short Form; NR, not reported; PCL-S, PTSD Checklist–Specific Stressor Version; PHQ-4, Patient Health Questionnaire – 4; PHQ-9, Patient Health Questionnaire – 9; PSI, Parenting Stress Index; PSQ, Perceived Stress Questionnaire; PSS, Perceived Stress Scale; PTSD, post-traumatic stress disorder; RDQ, Remission from Depression Questionnaire; RoB: risk of bias; SAAS, Social Appearance Anxiety Scale; SCID-I, Structured Clinical Interview for DSM Axis I Disorders; SCP, self-critical perfectionism; SCS, Self-Compassion Scale; SMFQ, Short Mood and Feelings Questionnaire; SMS, Short Message Service; SPIN, Social Phobia Inventory; SPS, Social Phobia Scale; STAI, Spielberger State-Trait Anxiety Inventory; TAU, treatment as usual; ZSDS; Zung Self-Rating Depression Scale