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. 2023 May 22;15:1173221. doi: 10.3389/fnagi.2023.1173221

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Copyright © 2023 Han, Zhou, Zhang, Jiao, Hu, Zhang, Wang, Lou and Bai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The ALPS-index was negatively correlated with age. (A,B) ALPS-index values were significantly lower in the older group (n = 11) than in the younger group [n = 11, (A)] in the group analysis and significantly negatively correlated with age in the linear regression analysis (B). (C) The ALPS-index was negatively correlated (near significance) with the AD_low–b of the MCA SAS. Group analysis was performed using Student’s t-test. ns: non-significant (p ≥ 0.05), ****p < 0.0001.