Table 2.
Comparison of the methods of synthesis of imidazolines based on reactions of benzaldehyde and ethylenediamine.
| Entry | Reagent | Solvent | Temp. (oC) | Time (min) | Yields (%) | Ref. |
|---|---|---|---|---|---|---|
| 1 | H2O2, NaI, MgSO4 | t-BuOH | 80 | 30 | 96 | Bai et al., (2011) |
| 2 | K4Fe(CN)6 | H2O | r.t | 30 | 85 | Shaikh et al. (2012) |
| 3 | a HPW, b TBAB | H2O | 80 | 120 | 93 | Liu et al. (2019) |
| 4 | c NBS | dry TBME or CH2Cl2 | 0 | 30 | 99 | Fujioka et al. (2007) |
| 5 | I2/KI/K2CO3 | H2O | 90 | 30 | 90 | Gogoi and Konwar, 2006 |
| 6 | I2,K2CO3 | t-BuOH | 70 | 180 | 100 | Ishihara and Togo (2007a) |
| 7 | d CAN | Dry-CH2Cl2 | Reflux | 15 | 90 | Kumar and Joshi (2007) |
| 8 | NBS | H2O | 65–70 | 12 | 99 | Sant’ Anna et al., 2009 |
| 9 | NBSac | CH2Cl2 | r.t | 20 | 96 | This work |
Tungstophosphoric acid.
Tetrabutylammonium bromide.
N-bromosuccinimide.
Ceric ammonium nitrate.