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. 2023 May 22;11:1190637. doi: 10.3389/fbioe.2023.1190637

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Copyright © 2023 He, Jiang, Zhang, Li, Hu, Hua, Cai, Mo and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of Nuclear Mismatch Repair Proteins between mCRC Patient and PDO Samples. Immunohistochemistry of the nuclear mismatch repair (MMR) proteins MLH1, MSH6, MSH2, and PMS2. (A) Displayed are two patients with proficient MMR, CRC-P8 and CRC-P14, and two patients with deficient MMR, (B) CRC-P4, MLH1 (−) /PMS2 (−); (C) CRC-P24, MSH2 (−)/MSH6 (−). Scale bar, 100 μm.