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. 2023 May 29;40(2):82–91. doi: 10.4274/tjh.galenos.2023.2022.0435

Figure 4.

Figure 4

CircPVT1 knockdown decreased the expression of CXCR4, a downstream target of c-Myc. a) The efficiencies of c-Myc knockdown and overexpression in THP-1 cells were verified by RT-qPCR. b) c-Myc knockdown and overexpression affected CXCR4 mRNA levels. c) c-Myc knockdown and overexpression affected CXCR4 protein expression. CircPVT1 knockdown also reduced CXCR4 mRNA d) and protein e) expression, while simultaneous overexpression of c-Myc partially reversed this effect. *: p<0.05, **: p<0.01.