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c-Myc overexpression partially reversed the effects of circPVT1 knockdown on cell proliferation, migration, and apoptosis. THP-1 cells were transfected with small interfering RNA targeting circPVT1 (si-circPVT1) or si-circPVT1 + c-Myc overexpression plasmid (oe-Myc). CCK-8 assays a), trans-well assays b), and annexin V/PI staining assays (c, d) were then performed to evaluate cell proliferation, migration, and apoptosis, respectively. *: p<0.05, **: p<0.01.
