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. 2023 Mar 6;102(6):102624. doi: 10.1016/j.psj.2023.102624

Figure 4.

Figure 4

(A) Results of UMAP dimensionality reduction analysis. The X-axis and Y-axis represent 2 dimensions after dimensionality reduction by the UMAP method. Each dot represents a cell, and cells with similar expression patterns will gather into a cell cluster. Different colors refer to a different cell cluster. Clusters 0, 3, 4, 6, and 9 were identified as ciliated epithelium. Clusters 1, 10, and 13 were identified as nonciliated epithelium. Clusters 2 and 5 were identified as red blood cells. Cluster 7 was identified as fibroblasts. Clusters 8, 15, and 16 were identified as immune-related cells. Cluster 11 was identified as SST epithelium. Clusters 12 and 14 were unknown cell types. (B) Expression patterns of DCN, MKI67, SLC14A2, JCHAIN, HEY1, and CA8 in different cell clusters. The X-axis and Y-axis represent 2 dimensions after dimensionality reduction by the UMAP method. Each dot refers to a cell, and the depth of color represents the expression of corresponding genes. (C) Gene expression heatmap of top 200 DEGs derived from different clusters. Each row represents the cell cluster, and the names of cell clusters have been marked on the left. Different colors represent the gene expression level.