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. 2023 May 10;52:137–144. doi: 10.1016/j.euros.2023.04.015

Table 2.

Proportion of patients with metastatic disease for a given size of primary tumor

Tumor size (cm) Any RCC
% of patients
(95% CI)
ccRCC
% of patients
(95% CI)
pRCC
% of patients
(95% CI)
chRCC
% of patients
(95% CI)
sarcRCC
% of patients
(95% CI)
0.5–<2 2.7% (2.5–3.0%) 1.6% (1.3–1.9%) 1.2% (0.9–1.7%) 0.6% (0.3–1.5%) 34.1% (26.3–42.7%)
2–<3 2.5% (2.3–2.7%) 1.5% (1.3–1.7%) 1.3% (1.0–1.7%) 0.8% (0.4–1.4%) 22.8% (16.8–30.2%)
3–<4 4.0% (3.8–4.3%) 2.5% (2.3–2.8%) 2.5% (2.0–3.0%) 0.9% (0.5–1.5%) 25.6% (20.0–32.1%)
4–<5 7.1% (6.8–7.4%) 4.8% (4.5–5.2%) 4.0% (3.4–4.9%) 1.1% (0.7–1.9%) 32.0% (27.0–37.4%)
5–<6 11.5% (11.0–12.0%) 8.1% (7.5–8.6%) 6.5% (5.5–7.7%) 2.2% (1.4–3.4%) 41.3% (36.4–46.4%)
6–<7 16.7% (16.1–17.3%) 12.6% (11.9–13.4%) 9.4% (7.8–11.1%) 2.4% (1.4–3.8%) 45.0% (40.4–49.7%)
7–<8 22.6% (21.8–23.4%) 17.9% (17.0–18.9%) 12.1% (10.1–14.5%) 3.5% (2.1–5.6%) 45.9% (41.3–50.6%)
8–<10 30.0% (29.2–30.7%) 25.4% (24.5–26.3%) 16.7% (14.6–19.0%) 4.9% (3.5–6.7%) 53.5% (50.1–56.8%)
10–<12 40.3% (39.3–41.4%) 36.5% (35.1–37.8%) 23.4% (20.2–26.8%) 6.0% (4.2–8.6%) 59.0% (55.2–62.6%)
12–<14 46.1% (44.7–47.5%) 42.7% (40.9–44.6%) 28.4% (24.1–33.1%) 12.3% (9.0–16.4%) 64.9% (60.4–69.2%)
14–<17 49.3% (47.7–51.0%) 47.9% (45.5–50.3%) 31.9% (27.1–37.1%) 13.2% (9.5–18.0%) 65.1% (60.1–69.7%)
17–≤20 49.4% (46.7–52.2%) 52.4% (47.9–56.9%) 31.9% (25.5–39.1%) 16.4% (10.7–24.2%) 62.1% (55.0–68.7%)

ccRCC = clear cell RCC; chRCC = chromophobe RCC; CI = confidence interval; pRCC = papillary RCC; RCC = renal cell carcinoma; sarcRCC = sarcomatoid RCC and RCC with sarcomatoid features.