Comparison 2. Experimental studies with synthetic tetrahydrocannabinol (THC) analogue versus placebo for individuals with cancer pain.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
2.1 Mean pain intensity	4	301	Std. Mean Difference (IV, Random, 95% CI)	‐0.98 [‐1.36, ‐0.60]
2.1.1 Synthetic THC analogue 5 mg and 10 mg	4	193	Std. Mean Difference (IV, Random, 95% CI)	‐0.77 [‐1.19, ‐0.35]
2.1.2 Synthetic THC analogue 15 mg and 20 mg	2	108	Std. Mean Difference (IV, Random, 95% CI)	‐1.42 [‐2.23, ‐0.62]