Table 21:

Budget Impact Analysis Results—Scenario Analyses

Scenario	Budget impact, $ milliona
	Year 1	Year 2	Year 3	Year 4	Year 5	Totalb	% Changec
Reference case	0.51	1.01	1.53	2.06	2.61	7.73	0%
1. Low volume of localizations	0.46	0.91	1.37	1.82	2.28	6.84	-11%
2. High volume of localizations	0.55	1.11	1.70	2.31	2.94	8.61	11%
3. Increased uptake of wire-free, nonradioactive localization techniques	0.63	1.27	1.92	2.59	3.28	9.70	26%
4. Decreased uptake of wire-free, nonradioactive localization techniques	0.38	0.75	1.14	1.54	1.94	5.75	-26%
5. Manually loaded radioactive seeds	0.53	1.06	1.61	2.18	2.76	8.14	5%
6. Capital expenditures scenario at a representative site	0.56	1.11	1.68	2.26	2.86	8.47	10%
7. Capital expenditures scenario at a high-volume site	0.54	1.08	1.63	2.19	2.77	8.22	7%
8. Capital expenditures scenario at a low-volume site	0.62	1.23	1.85	2.49	3.15	9.34	21%
9. Different re-excision rate for each localization technique	0.31	0.62	0.93	1.25	1.58	4.69	-39%
10. Higher cost to acquire wire-free, nonradioactive markers or seeds	0.62	1.25	1.89	2.54	3.21	9.51	23%
11. Lower cost to acquire wire-free, nonradioactive markers or seeds	0.39	0.78	1.18	1.59	2.01	5.95	-23%
12. Replacing biopsy clip placed after core biopsy with MRI-compatible wire-free, nonradioactive marker or seed	0.49	0.99	1.49	2.01	2.54	7.53	-3%

^aIn 2022 Canadian dollars.

^bResults may appear inexact due to rounding.

^cPercent change calculated as the total budget impact of the scenario analysis divided by the total budget impact of the reference case.