Fig. 1.

A 6-month subject’s T1w image, T2w image, T1w/T2w image, manual delineation map of 12 subcortical structures, manual delineation map with inner and outer boundaries, and the ground-truth signed distance map (SDM) of the thalamus. Due to the low tissue contrast of the 6-month infant brain MR images, the subcortical boundaries are ambiguous in the T1w image and T2w image, while the T1w/T2w image has the enhanced tissue contrast, and thus the boundaries are more distinguishable (pointed by yellow arrows). We performed the commonly used Euclidean distance transforms to create the subcortical ground-truth SDMs from the manual delineation maps.