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. 2023 Apr 12;2023(2):22-0362. doi: 10.1530/EDM-22-0362

Table 1.

Clinical characteristics of the family.

Characteristic Proband Mother Grandfather
Age (years) 17 50 87
Height (cm) 165 156 165
Body weight (kg) 52.6 56 45.3
Body mass index (kg/m2) 19.3 23 16.6
FPG (mg/dL) 75 107 117
Insulin (μU/mL) 50 37 125.3*
C-peptide (ng/mL) 2.08 2.62 7.6
Proinsulin (pmol/L) 5.4 ND ND
HbA1c (%) 5.6 6.5 6.4
Triglycerides (mg/dL) 87 114 109
HDL cholesterol (mg/dL) 70 72 43
LDL cholesterol (mg/dL) 82 125 96
Anti-IR antibody None ND ND
Birth weight (g) 3000 3900 Unknown
Acanthosis nigricans None None None
Hirsutism None None None
Diabetes treatment None None DPP4I
Estimated diabetes onset No diabetes 50 years 77 years

*Postprandial value.

Anti-IR, anti-insulin receptor; BMI, body mass index; DPP4I, dipeptidyl peptidase 4 inhibitor; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ND, not determined.