Table 1.
Characteristic | Proband | Mother | Grandfather |
---|---|---|---|
Age (years) | 17 | 50 | 87 |
Height (cm) | 165 | 156 | 165 |
Body weight (kg) | 52.6 | 56 | 45.3 |
Body mass index (kg/m2) | 19.3 | 23 | 16.6 |
FPG (mg/dL) | 75 | 107 | 117 |
Insulin (μU/mL) | 50 | 37 | 125.3* |
C-peptide (ng/mL) | 2.08 | 2.62 | 7.6 |
Proinsulin (pmol/L) | 5.4 | ND | ND |
HbA1c (%) | 5.6 | 6.5 | 6.4 |
Triglycerides (mg/dL) | 87 | 114 | 109 |
HDL cholesterol (mg/dL) | 70 | 72 | 43 |
LDL cholesterol (mg/dL) | 82 | 125 | 96 |
Anti-IR antibody | None | ND | ND |
Birth weight (g) | 3000 | 3900 | Unknown |
Acanthosis nigricans | None | None | None |
Hirsutism | None | None | None |
Diabetes treatment | None | None | DPP4I |
Estimated diabetes onset | No diabetes | 50 years | 77 years |
*Postprandial value.
Anti-IR, anti-insulin receptor; BMI, body mass index; DPP4I, dipeptidyl peptidase 4 inhibitor; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ND, not determined.