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. 2022 Oct 21;18(9):719–728. doi: 10.4244/EIJ-D-22-00043

Table 3. Five-year absolute MACE and TVF rates across groups defined by abnormal/normal CFR and MR.

Total CFR ≥2.5 CFR <2.5
MR low MR high Total MR low MR high Total
MACE at 5 years, n (%) 96 (9.1) 23 (5.8) 6 (6.3) 29 (5.5) 42 (12.6) 25 (11.2) 67 (11.7)
All-cause death 37 (3.5) 10 (2.5) 1 (1.1) 11 (2.1) 16 (4.8) 10 (4.5) 26 (4.6)
Acute myocardial infarction 13 (1.2) 4 (1.0) 1 (1.1) 5 (1.0) 2 (0.6) 6 (2.7) 8 (1.4)
Urgent revascularisation 90 (4.3) 25 (6.3) 7 (7.4) 32 (6.0) 35 (10.5) 23 (10.3) 58 (10.2)
TVF at 5 years, n (%) 94 (6.0) 27 (4.3) 4 (2.5) 31 (3.9) 40 (8.3) 23 (7.6) 63 (8.2)
Cardiac death 32 (2.0) 9 (1.4) 0 (0) 9 (1.1) 14 (2.9) 9 (3.0) 23 (2.9)
Acute myocardial infarction (target vessel) 18 (1.2) 5 (0.8) 1 (0.6) 6 (0.7) 5 (1.0) 7 (2.3) 12 (1.6)
Urgent revascularisation
(target vessel)
81 (5.2) 25 (4.1) 4 (2.5) 29 (3.7) 31 (6.5) 21 (7.1) 52 (6.8)
Data presented as median [25th- 75th IQ] or n (%). CFR: coronary flow reserve; MACE: major adverse cardiac events; and MR: microvascular resistance; TVF: target vessel failure