Table 2.
Univariable and Multivariable Models of the Association Between RE and/or AL and POAG
| Univariable Analysis | Multivariable Analysis | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Parameter | OR (CI) | P | Model A (RE) OR (CI) | P | Model B (AL) OR (CI) | P | Model C (RE + AL) OR (CI) | P | SRC |
| Sex (male) | 1.56 (1.27–1.92) | <0.001 | 1.56 (1.24–1.97) | <0.001 | 1.37 (1.08–1.73) | 0.008 | 1.41 (1.11–1.78) | 0.004 | 0.17 |
| Age (y) | 1.06 (1.05–1.07) | <0.001 | 1.06 (1.05–1.08) | <0.001 | 1.06 (1.05–1.08) | <0.001 | 1.06 (1.05–1.08) | <0.001 | 0.50 |
| Ethnicity/race (Latino) | 1.55 (1.26–1.92) | <0.001 | 2.07 (1.62–2.65) | <0.001 | 2.14 (1.67–2.74) | <0.001 | 2.25 (1.75–2.90) | <0.001 | 0.41 |
| FHG (yes) | 1.73 (1.24–2.36) | 0.001 | 1.68 (1.18–2.34) | 0.003 | 1.65 (1.16–2.31) | 0.004 | 1.63 (1.14–2.28) | 0.005 | 0.14 |
| IOP (per 1-mmHg increase) | 1.17 (1.14–1.20) | <0.001 | 1.16 (1.13–1.20) | <0.001 | 1.17 (1.13–1.20) | <0.001 | 1.17 (1.13–1.20) | <0.001 | 0.50 |
| AL (per 1-mm increase) | 1.29 (1.20–1.38) | <0.001 | — | — | 1.37 (1.26–1.48) | <0.001 | 1.27 (1.14–1.41) | <0.001 | 0.30 |
| RE (D) | |||||||||
| No myopia (>−0.5) | REF | — | REF | — | — | — | REF | — | — |
| Mild myopia (≤−0.5 to >−3) | 1.41 (1.08–1.83) | 0.01 | 1.54 (1.15–2.04) | 0.003 | — | — | 1.35 (1.00–1.81) | 0.04 | 0.12 |
| Moderate myopia (≤−3 to >−6) | 2.00 (1.37–2.85) | <0.001 | 2.47 (1.60–3.71) | <0.001 | — | — | 1.64 (1.02–2.58) | 0.04 | 0.12 |
| High myopia (≤−6) | 3.58 (2.41–5.17) | <0.001 | 3.94 (2.39–6.25) | <0.001 | — | — | 1.81 (0.97–3.27) | 0.06 | 0.11 |
Model A shows the role of RE, Model B shows the role of AL, and Model C shows the roles of AL and RE together. REF, reference.