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. 2023 Jun 1;64(7):4. doi: 10.1167/iovs.64.7.4

Table 3.

Univariable and Multivariable Models of the Association Between AL Components and RE and POAG

Univariable Analysis Multivariable Analysis
Parameter OR (CI) P Model D (CCT + ACD + LT + VCD) OR (CI) P SRC Model E (VCD + RE) OR (CI) P SRC
Sex (male) 1.56 (1.27–1.92) <0.001 1.36 (1.07–1.73) 0.01 0.15 1.46 (1.15–1.84) 0.002 0.18
Age (year) 1.06 (1.05–1.07) <0.001 1.07 (1.05–1.08) <0.001 0.52 1.07 (1.05–1.08) <0.001 0.52
Ethnicity/race (Latino) 1.55 (1.26–1.92) <0.001 2.00 (1.48–2.72) <0.001 0.35 2.38 (1.83–3.10) <0.001 0.43
FHG (yes) 1.73 (1.24–2.36) 0.001 1.71 (1.19–2.40) 0.002 0.15 1.67 (1.17–2.34) 0.004 0.15
IOP (per 1-mmHG increase) 1.17 (1.14–1.20) <0.001 1.20 (1.16–1.24) <0.001 0.58 1.19 (1.15–1.23) <0.001 0.55
CCT (per 1-µm increase) 1.00 (0.99–1.00) 0.13 1.00 (0.99–1.00) 0.04 −0.13
ACD (per 1-mm increase) 1.15 (1.01–1.30) 0.02 1.43 (1.00–2.04) 0.05 0.14
LT (per 1-mm increase) 1.14 (0.92–1.39) 0.22 1.29 (0.99–1.66) 0.05 0.12
VCD (per 1-mm increase) 1.23 (1.15–1.32) <0.001 1.37 (1.24–1.50) <0.001 0.39 1.24 (1.11–1.39) <0.001 0.27
RE (D)
 No myopia (>−0.5) REF REF REF
 Mild myopia (≤−0.5 to >−3) 1.41(1.08–1.83) 0.01 1.36 (1.00–1.83) 0.04 0.12
 Moderate myopia (≤−3 to >−6) 2.00 (1.37–2.85) <0.001 1.69 (1.04–2.65) 0.03 0.12
 High myopia (≤−6) 3.58 (2.41–5.17) <0.001 2.12 (1.14–3.82) 0.02 0.13

Model D shows the role of AL components, and Model E shows the roles of VCD and RE together. VCD = AL – CCT – ACD – LT.