Table 3.
Univariable and Multivariable Models of the Association Between AL Components and RE and POAG
| Univariable Analysis | Multivariable Analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| Parameter | OR (CI) | P | Model D (CCT + ACD + LT + VCD) OR (CI) | P | SRC | Model E (VCD + RE) OR (CI) | P | SRC |
| Sex (male) | 1.56 (1.27–1.92) | <0.001 | 1.36 (1.07–1.73) | 0.01 | 0.15 | 1.46 (1.15–1.84) | 0.002 | 0.18 |
| Age (year) | 1.06 (1.05–1.07) | <0.001 | 1.07 (1.05–1.08) | <0.001 | 0.52 | 1.07 (1.05–1.08) | <0.001 | 0.52 |
| Ethnicity/race (Latino) | 1.55 (1.26–1.92) | <0.001 | 2.00 (1.48–2.72) | <0.001 | 0.35 | 2.38 (1.83–3.10) | <0.001 | 0.43 |
| FHG (yes) | 1.73 (1.24–2.36) | 0.001 | 1.71 (1.19–2.40) | 0.002 | 0.15 | 1.67 (1.17–2.34) | 0.004 | 0.15 |
| IOP (per 1-mmHG increase) | 1.17 (1.14–1.20) | <0.001 | 1.20 (1.16–1.24) | <0.001 | 0.58 | 1.19 (1.15–1.23) | <0.001 | 0.55 |
| CCT (per 1-µm increase) | 1.00 (0.99–1.00) | 0.13 | 1.00 (0.99–1.00) | 0.04 | −0.13 | — | — | — |
| ACD (per 1-mm increase) | 1.15 (1.01–1.30) | 0.02 | 1.43 (1.00–2.04) | 0.05 | 0.14 | — | — | — |
| LT (per 1-mm increase) | 1.14 (0.92–1.39) | 0.22 | 1.29 (0.99–1.66) | 0.05 | 0.12 | — | — | — |
| VCD (per 1-mm increase) | 1.23 (1.15–1.32) | <0.001 | 1.37 (1.24–1.50) | <0.001 | 0.39 | 1.24 (1.11–1.39) | <0.001 | 0.27 |
| RE (D) | ||||||||
| No myopia (>−0.5) | REF | — | — | — | — | REF | REF | |
| Mild myopia (≤−0.5 to >−3) | 1.41(1.08–1.83) | 0.01 | — | — | — | 1.36 (1.00–1.83) | 0.04 | 0.12 |
| Moderate myopia (≤−3 to >−6) | 2.00 (1.37–2.85) | <0.001 | — | — | — | 1.69 (1.04–2.65) | 0.03 | 0.12 |
| High myopia (≤−6) | 3.58 (2.41–5.17) | <0.001 | — | — | — | 2.12 (1.14–3.82) | 0.02 | 0.13 |
Model D shows the role of AL components, and Model E shows the roles of VCD and RE together. VCD = AL – CCT – ACD – LT.