TABLE 1.
Total | No Plaques | Plaques | P | |
---|---|---|---|---|
Ν = 284 | n = 48 | n = 236 | ||
Age, yr | 60.0 (56.3–66.0) | 57.7 (55.1–61.3) | 60.6 (56.7–66.1) | 0.008 |
BMI, kg·m−2 | 24.5 (22.9–26.7) | 24.0 (22.4–25.2) | 24.7 (23.1–26.8) | 0.024 |
Systolic BP, mm Hg | 140 ± 18 | 135 ± 15 | 140 ± 18 | 0.057 |
Current smoker, n (%) | 9 (3%) | 1 (2%) | 8 (3%) | 0.64 |
Total cholesterol, mmol·L−1 | 5.2 ± 0.9 | 5.2 ± 0.8 | 5.2 ± 0.9 | 0.86 |
Hypertension, n (%) | 36 (13%) | 5 (10%) | 31 (13%) | 0.61 |
Diabetes mellitus, n (%) | 9 (3%) | 2 (4%) | 7 (3%) | 0.67 |
CVD, n (%) | 6 (2%) | 1 (2%) | 5 (2%) | 0.99 |
Family history of CVD, n (%) | 100 (35%) | 9 (19%) | 91 (39%) | 0.009 |
CAC score, Agatston units | 31 (0–132) | 0 (0–0) | 55 (7–184) | <0.001 |
Obstructive CAD, n (%) | 32 (11%) | 0 (0%) | 32 (14%) | 0.007 |
MET·h·wk−1 | 40.5 (25.9–56.6) | 38.5 (21.3–61.3) | 40.7 (26.8–56.4) | 0.69 |
AGE | ||||
Free CML, nmol·L−1 | 112 (90–135) | 117 (92–141) | 110 (89–134) | 0.56 |
Free CEL, nmol·L−1 | 58 (48–72) | 57 (47–76) | 58 (48–72) | 0.75 |
Free MG-H1, nmol·L−1 | 329 (220–465) | 278 (218–478) | 332 (220–449) | 0.50 |
CML, nmol·L−1 | 3378 (3023–3720) | 3387 (3140–3644) | 3373 (3012–3726) | 0.88 |
CEL, nmol·L−1 | 1599 (1337–1910) | 1595 (1356–1818) | 1599 (1326–1918) | 0.77 |
MG-H1, nmol·L−1 | 1237 (1106–1383) | 1215 (1142–1371) | 1242 (1100–1383) | 0.71 |
Dicarbonyl compounds | ||||
MGO, nmol·L−1 | 439 (387–491) | 433 (392–471) | 440 (385–497) | 0.62 |
GO, nmol·L−1 | 516 (456–592) | 492 (425–547) | 520 (464–600) | 0.046 |
3-DG, nmol·L−1 | 1201 (1123–1268) | 1222 (1163–1280) | 1197 (1120–1264) | 0.23 |
Data are presented as mean ± SD, median (interquartile range), or n (%).
BMI, body mass index; BP, blood pressure; MET, metabolic equivalent; CML, Nε-(carboxymethyl)-lysine; CEL, Nε-(1-carboxyethyl)-lysine; MG-H1, Nδ-(5-hydro-5-methyl-4-imidazolon-2-yl)-ornithine; MGO, methylglyoxal; GO, glyoxal; 3-DG, 3-deoxyglucosone (3-DG).