Table 2.

Effect of S. striata aqueous (SSAE) and hydroalcoholic (SSHE) extracts on microscopic parameters of colitis in rats

Groups/dose (mg/kg)	Inflam. severity (0-3)	Inflam. extent (0-3)	Leucocyte infiltration (0-3)	Crypt Damage (0-4)	Total colitis index (0-13)
Normal	0.0 (0-0)	0.0 (0-0)	0.0 (0-0)	0.0 (0-0)	0.0 (0-0)
Control colitis	3.0 (3-3) ###	3.0 (3-3) ###	3.0 (2-3) ###	4.0 (3-4) ###	12.5 (12-13) ###
SSAE 150	3.0 (2-3)	3.0 (2-3)	3.0 (2-3)	3.5 (2-4)	11.6 (9-13)
SSAE 300	3.0 (2-3)	3.0 (2-3)	2.5 (1-3)	3.0 (2-4)	10.8 (7-13)
SSAE 600	2.5 (1-3)	2.5 (2-3)	2.0 (1-3)	3.0 (2-3) *	9.0 (6-12)*
SSHE 150	2.0 (1-2)***	2.0 (1-3)*	2.0 (1-2)*	2.5 (1-3)*	8.6 (4-10)**
SSHE 300	1.5 (0-2)***	2.0 (1-2)*	1.0 (1-2)***	2.0 (1-3)**	6.3 (3-7) ***
SSHE 600	1.0 (0-2)***	1.0 (1-2)***,+	1.0 (1-1)***	1.5 (1-2)***,+	4.6 (3-7) ***+
Dex.1	1.0 (0-1)***	1.0 (0-1)***	1.0 (0-1)***	1.0 (1-1)***	3.1 (1-5) ***
Mes.100	2.0 (1-3)*	1.5 (1-3)**	2.0 (1-2)*	3 (2-3)*	8.4 (5-11) **

Data are presented as Means±SEM (n=6). Dex. (Dexamethasone), Mes. (Mesalazine). The differences between groups were calculated based on Mann-Whitney test. *P<0.05, **P<0.01, ***P<0.001 represent significant difference compared to control group, ⁺P<0.05 represent significant difference compared to SSAE 600 mg/kg, ^###P<0.001 represent significant difference compared to normal group