Table 2.
Vessel median diameter as a prognostic factor in multivariable analysis of the “whole section” cohort in ER+ breast cancer subset
| Variables | Multivariable analysis | |
|---|---|---|
| HR (95% CI) | p value | |
| Vessel median diameter | ||
| Low | 1 (reference) | |
| High | 5.63 (1.48–21.48) | 0.01 |
| Age at diagnose | ||
| ≤ 60 | 1 (reference) | |
| > 60 | 0.36 (0.11–1.15) | 0.08 |
| Tumor size | ||
| ≤ 20 mm | 1 (reference) | |
| > 20 mm | 0.64 (0.16–2.59) | 0.53 |
| Histologic grade | ||
| Grade 1 | 1 (reference) | |
| Grade 2 | 0.47 (0.11–2.03) | 0.31 |
| Grade 3 | 0,95 (0.24–3.78) | 0.94 |
| Lymph node status | ||
| N0 | 1 (reference) | |
| N1 | 5.89 (1.8–19.28) | 0.003 |
| Progesterone receptor status | ||
| + | 1 (reference) | |
| − | 2.76 (0.83–9.15) | 0.097 |
| HER2 status | ||
| − | 1 (reference) | |
| + | 1.88 (0.48–7.35) | 0.36 |
The 86 ER + breast cancer cases of the “whole section” cohort were included in the regression model. Vessel median size variable was dichotomized as “low (0–50%)” and “high (>50%)” group based on the median value
p value are calculated based on Wald test; HR is based on cause-specific Cox-regression model
HR hazard ratio, CI confidence interval, HER2 human epidermal growth factor 2, ER estrogen receptor, PR progesterone receptor