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. 2023 Jun 5;14:3239. doi: 10.1038/s41467-023-38994-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Allele-dependent differences in gene expression of TEC, the strongest unique response expression quantitative trait locus (reQTL) after 3 h N. meningitidis (Nm) stimulation. Differences in regression slope with A. fumigatus (Af): p_Nm-Af = 4.41 × 10⁻²² and S. aureus (Sa): p_Nm-Sa = 1.98 × 10⁻¹⁹. b Allele-dependent differences in expression of IRF7, a unique reQTL-regulated gene for A. fumigatus exposure (6 h) with differences in regression slope for N. meningitidis (p_Af-Nm = 6.5 × 10⁻¹⁰) and S. aureus (p_Af-Sa = 1.9 × 10⁻⁰⁴). Bonferroni corrected p-values from z test of differences in regression coefficients to unstimulated control (ctrl) are indicated. Ctrl: unstimulated. Source data are provided as a Source Data file.