Table 2.

Assumed dose-response (D-R) models based on four considered scenarios to assess the human exposure risk to antibiotic resistant (AR) Escherichia coli [26].

Scenarios	Host and response type	D-R model	Model parameters for infection endpoints
1: AR E. coli D-R model is similar to non AR E. coli	Human, diarrhoea	Beta-poisson model $P_d=1-{\left(1+\frac{\mathrm{N}}{\beta }\right)}^{-\alpha }$	α = 0.1705, β = 1.61 × 106
2: AR E. coli D-R model is similar to gentamicin resistant E. coli	Human, diarrhoea	Beta-poisson model $P_d=1-{\left(1+\frac{\mathrm{N}}{\beta }\right)}^{-\alpha }$	α = 0.16, β = 1.41 × 106
3: AR E. coli D-R model is similar to most infectious/virulent bacteria (E. coli O157:H7/Shigella)	Human, severe diarrhoea	Beta-poisson model $P_d=1-{\left(1+\frac{\mathrm{N}}{\beta }\right)}^{-\alpha }$	α = 0.277, β = 2.38 × 102
4: AR E. coli D-R model is similar to most persistent bacteria (Clostridium perfringens)	Human, vomiting, abdominal cramps and diarrhoea within 24 h	Exponential model $P_d=1-{e^{-}}^{\mathrm{r}\times \mathrm{N}}$	r = 1.82 × 10−11