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. Author manuscript; available in PMC: 2024 Jun 6.
Published before final editing as: Gut. 2022 Dec 6:gutjnl-2022-328174. doi: 10.1136/gutjnl-2022-328174

Figure 1.

Figure 1.

Risk and PAR of (a) Crohn’s disease and (b) ulcerative colitis according to modifiable risk scores. Reference level for UC set to 0–2 given low number of scores 0–1. a Cox models stratified by age (months), time-period (2-year intervals), and cohort (NHS, NHSII, or HPFS), and adjusted for appendectomy (yes/no), and family history of IBD (yes/no). b PAR for binary comparison between high-MRS (2+ risk factors for CD or 3+ risk factors for UC) and low-MRS (reference), adjusted for age (<40, 40 ≤ age <60, ≥ 60 years), cohort (NHS, NHSII, HPFS), appendectomy (yes/no) and family history of IBD (yes/no). CD Crohn’s Disease. CI Confidence Interval. aHR Multivariable-adjusted Hazard Ratio. MRS Modifiable Risk Score. PAR Population Attributable Risk. UC Ulcerative Colitis.