Table 4.
Exosome-related studies in the clinical trial phase.
| Study title | Study type | Intervention model | Estimated enrollment | Intervention | Status | Phase | Last update | NTC number |
|---|---|---|---|---|---|---|---|---|
| iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation | Treatment | Single group assignment | 28 participants | Exosomes with KRAS G12D siRNA | Recruiting | Phase 1 | 2022 | NCT03608631 |
| ExoLuminate Study for Early Detection of Pancreatic Cancer | Diagnostic | Observational cohort |
1,000 participants | N/A | Not yet recruiting | N/A | 2022 | NCT05625529 |
| Diagnostic Accuracy of Circulating Tumor Cells (CTCs) and Onco-exosome Quantification in the Diagnosis of Pancreatic Cancer -PANC-CTC | Diagnostic | Observational cohort |
52 participants | N/A | Completed | N/A | 2018 | NCT03032913 |
| Circulating Extracellular Exosomal Small RNA as Potential Biomarker for Human Pancreatic Cancer | Diagnostic | Single group assignment | 102 participants | Venous sampling | Unknown | N/A | 2020 | NCT04636788 |
| New Biomarkers in Pancreatic Cancer Using EXPEL Concept (PANEXPEL) | Diagnostic | Observational cohort |
200 participants | N/A | Recruiting | N/A | 2022 | NCT03791073 |